| Practice size | Small (reference) | 2327 | . | 0.0097 |
| Medium | 4465 | 1.135 (1.00 - 1.29) | ||
| Large | 1631 | 1.33 (1.11 - 1.60) | ||
| Practice Volume | <50 (reference) | 2994 | . | <0.0001 |
| 50 - 99 | 4007 | 0.80 (0.71 - 0.91) | ||
| 100 - 149 | 824 | 0.94 (0.77 - 1.15) | ||
| 150+ | 598 | 0.60 (0.41 - 0.75) | ||
| Smoking Status | Current (reference) | 1631 | . | |
| Former | 5439 | 1.35 (1.19 - 1.53) | <0.0001 | |
| Never | 1353 | 2.00 (1.70 - 2.36) | ||
| Sex | Male (reference) | 4402 | . | 0.0005 |
| Female | 4021 | 1.19 (1.08 - 1.30) | ||
| Race | White (reference) | 7345 | . | 0.0769 |
| Black | 700 | 0.97 (0.82 - 1.16) | ||
| Asian | 266 | 1.30 (0.99 - 1.72) | ||
| Other | 112 | 1.47 (0.97 - 2.22) | ||
| Year of Diagnosis | 2012 (reference) | 952 | . | <0.0001 |
| 2013 | 1403 | 1.34 (1.11 - 1.63) | ||
| 2014 | 1479 | 1.86 (1.54 - 2.24) | ||
| 2015 | 1579 | 2.56 (2.13 - 3.08) | ||
| 2016 | 1663 | 3.10 (2.57 - 3.72) | ||
| 2017 | 1347 | 3.77 (3.11 - 4.56) |