Modality

Biological Measure

Resolution

Cost in US$

Clinical Development

White light endoscopy

Surface Morphology and Vasculature

1 mm

4 - 13,000

Standard of Care

Fluorescence and Reflectance Spectroscopy

Redox Ratio, Collagen and Elastin Remodelling

1 mm

30,000

Additive to Oral Exam, Bronchoscopy, Esophagoscopy, Colonoscopy

Narrow Band Imaging

Neovascularization

1 mm

13,000

Additive to Colonoscopy

Optical Coherence Tomography

Mucosal Stratification and Subsurface Tissue Morphology

5 - 15 microns

40 - 100,000

Clinical Approved in Ophthalmology, Clinical Trials in Other Organ Sites

Confocal Endomicroscopy

Subsurface Tissue and Cell Morphology

1 micron

70,000

Being Evaluated in Multiple Organ Sites