|
| Enrolled Patients N (%) | |||
| All patients N = 34 | BSG - 11 | HG - 13 | LG - 10 | |
| Characteristic |
|
|
|
|
| Age median | 10.4 years | 2.9 years | 3.8 years | 5.9 years |
| Age range | 0.8 - 17.8 years | 2.7 - 12.25 years | 3.3 - 17.8 years | 0.8 - 17.3 years |
| Male | 13 (35%) | 1 | 8 | 4 |
| Female | 21 (65%) | 10 | 5 | 6 |
| Ethnicity | W 32 (94%), B 1 (3%), M 1 (3%) | W (100%) | W 12 (92%), B 1 (8%) | W 9 (90%), M 1 (10%) |
| Median Karnofsky Performance Score | 80 baseline/80 last evaluation | 80 baseline/80 last evaluation | 80 baseline/70 last evaluation | 90 baseline/90 last evaluation |
| Tumor Histology |
|
|
|
|
| DIPG | 9 | 9 |
|
|
| BSG/midbrain (pilocytic astrocytoma) | 2 | 2 |
|
|
| GBM | 5 |
| 5 |
|
| Anaplastic oligodendroglioma | 1 |
| 1 |
|
| Gliosarcoma | 1 |
| 1 |
|
| Anaplastic astrocytoma | 3 |
| 3 |
|
| Anaplastic glioma | 1 |
| 1 |
|
| sPNET (medulloepithelioma) | 1 |
| 1 |
|
| PNET (medulloblastoma) | 1 |
| 1 |
|
| Astrocytoma | 2 |
|
| 2 |
| Pilocytic astrocytoma | 1 |
|
| 1 |
| Craniopharyngioma | 1 |
|
| 1 |
| Ganglioglioma | 2 |
|
| 2 |
| Ganglioma-desmoplastic infantile | 1 |
|
| 1 |
| Neurocytoma | 1 |
|
| 1 |
| Oligodendroglioma | 1 |
|
| 1 |
| Optic pathway | 1 |
|
| 1 |
| Prior treatment |
|
|
|
|
| None or biopsy only | 6 | 2 | 2 | 2 |
| SU | 16 | 1 | 8 | 7 |
| SU + CH + RT | 3 | 0 | 3 | 0 |
| CH | 2 | 1 | 0 | 1 |
| CH + RT | 3 | 3 | 0 | 0 |
| RT | 4 | 4 | 0 | 0 |
| SU + RT | 0 | 0 | 0 | 0 |