Cellular cycle phases

%G0/G1

%S

%G2/M

GLC-82 wild type

Control

35.8 ± 0.8

32.2 ± 0.7

32.0 ± 0.5

Simvastatin (30 µM)

61.4 ± 0.5

22.2 ± 0.6

16.4 ± 0.4

H₂O₂ (0.5 mM)

21.0 ± 0.6

39.7 ± 0.3

39.3 ± 0.7

H₂O₂ (0.5 mM) + simvastatin (30 µM)

55.2 ± 0.3

28.3 ± 0.2

16.5 ± 0.3

GLCshHDAC2

Control

58.1 ± 1.1

27.3 ± 0.7

14.6 ± 0.4

Simvastatin (30 µM)

76.0 ± 0.2

11.6 ± 0.8

12.4 ± 0.4

H₂O₂ (0.5 mM)

28.4 ± 0.4

39.5 ± 0.3

32.1 ± 0.3

H₂O₂ (0.5 mM) + simvastatin (30 µM)

65.2 ± 0.8

17.6 ± 0.5

17.2 ± 0.7