Group	Participant number	Adverse event	Severity	Treatment	Causal relation with the study substance	Reason for causal conclusion	Continuation or discontinuation of the trial
Group	Participant number	(symptom)	Severity	Treatment	Causal relation with the study substance	Reason for causal conclusion	Continuation or discontinuation of the trial
Active	1	Dental caries	Moderate	Yes	Not related	Occasional event due to an infectious disease and was probably not associated with the study substance.	continued
Placebo	1	Premenstrual syndrome	Mild	No	Not related	Occasional event due to an infectious disease and was probably not associated with the study substance.	continued
Placebo	1	Dental caries	Moderate	Yes	Not related	Occasional event due to an infectious disease and was probably not associated with the study substance.	continued