Intracellular cGMP (fmol/10⁴ cells)

Butyrate

0

1 µM

100 µM

Control

8.3 ± 0.8

7.2 ± 0.8

9.8 ± 1.7

Theophylline

7.4 ± 0.7

9.4 ± 1.2

9.2 ± 0.8

Theophylline + SNP

10.5 ± 1.0

13.1 ± 1.5

12.9 ± 1.6

Theophylline + NaNO₂

9.0 ± 0.7

11.0 ± 0.8

13.7 ± 1.5

Extracellular (fmol/10⁴ cells)

Butyrate

0

1 µM

100 µM

Control

12.1 ± 1.9

10.0 ± 1.4

13.4 ± 2.2

Theophylline

12.1 ± 1.5

13.2 ± 2.0

13.5 ± 2.1

Theophylline + SNP

13.7 ± 1.7

13.8 ± 1.7

15.7 ± 2.0

Theophylline + NaNO₂

11.1 ± 1.3

12.7 ± 1.6

10.5 ± 1.2