Drug/extract

Dose (mg/kg bwt)

Mean no. of writhes recorded (±SEM)

P-value

Percentage protection

Total crude extract

5.0

20.5 ± 9.8

0.0061*

−3.8

40.0

22.0 ± 3.0

0.0014*

−11.4

150.0

18.0 ± 1.5

0.0008*

8.9

600.0

17.8 ± 2.3

0.0012*

10.4

1000.0

4.3 ± 2.3

0.085

78.5

Diclofenac Na

10.0

0.25 ± 0.38

0.0083**

98.7

Normal saline

1.0ml

19.8 ± 4.3

0.0083*

0.0