GO Enrichment

Term

Description

Number

of gene

Genes found

Biological

Process

regulation of cell shape

4

MSN, MYH10, TPM1, MYH9

cell-cell adhesion

4

CTNNA1, TLN1, ANXA2, MYH9

signal transduction

4

ZYX, FLNB, IQGAP1, NDRG1

angiogenesis

5

CALD1, FLNA, ACTG1, ANXA2, MYH9

cell adhesion

5

MYH10, ZYX, CTNNA1, TLN1, MYH9

platelet aggregation

6

HSPB1, FLNA, MYL9, ACTG1, TLN1, MYH9

muscle contraction

6

CALD1, TPM3, TPM1, TPM4, UTRN, MYL6

cellular response to interferon-gamma

6

ACTR3, ZYX, ACTG1, FLNB, MYO1C, ACTR2

actin cytoskeleton organization

6

FLNA, PDLIM7, PFN1, FLNB, UTRN, ACTR2

actin filament organization

7

TPM3, TMSB4X, TPM1, ACTR3, TPM4, CTNNA1, MYO1C

Cellular components

myosin II complex

4

MYH10, MYL9, MYH9, MYL6

brush border

6

FLNA, ACTR3, FLNB, MYO1C, MYH9, MYL6

adherens junction

8

PDLIM7, MSN, ZYX, CTNNA1, TLN1, ANXA2, MYH9, NDRG1

stress fiber

10

TPM3, PDLIM7, MYH10, TPM1, ZYX, TPM4, MYL9, FLNB, MYO1C, MYH9

actin cytoskeleton

15

CALD1, TPM3, FLNA, PDLIM7, TPM1, ARPC4, ACTR3, ZYX, CTNNA1, ACTG1, FLNB, MYO1C, IQGAP1, ACTR2, MYH9

focal adhesion

15

HSPB1, FLNA, PDLIM7, MSN, ACTR3, ZYX, TPM4, PFN1, CTNNA1, ACTG1, FLNB, TLN1, IQGAP1, ACTR2, MYH9

extracellular exosome

22

HSPB1, TPM3, FLNA, MSN, MYH10, ARPC4, ACTR3, TPM4, PFN1, TAGLN2, ACTG1, FLNB, TLN1, ANXA2, KRT7, MYO1C, IQGAP1, UTRN, ACTR2, MYH9, MYL6, NDRG1

cytoskeleton

26

CALD1, HSPB1, TPM3, FLNA, TMSB4X, PDLIM7, MSN, TPM1, ARPC4, ACTR3, TAGLN, TUBA1B, KRT17, ZYX, TPM4, PFN1, TAGLN2, CTNNA1, MYL9, ACTG1, FLNB, TLN1, UTRN, ACTR2, MYH9, NDRG1

cytosol

29

CALD1, HSPB1, TPM3, FLNA, TMSB4X, PDLIM7, MSN, MYH10, DUSP23, TPM1, ARPC4, ACTR3, KRT17, ZYX, TPM4, PFN1, TAGLN2, CTNNA1, MYL9, ACTG1, FLNB, TLN1, KRT7, MYO1C, IQGAP1, ACTR2, MYH9, MYL6, NDRG1

cytoplasm

31

CALD1, HSPB1, TPM3, FLNA, TMSB4X, PDLIM7, MSN, MYH10, DUSP23, TPM1, ARPC4, ACTR3, TAGLN, TUBA1B, KRT17, ZYX, TPM4, PFN1, CTNNA1, MYL9, ACTG1, FLNB, TLN1, ANXA2, KRT7, MYO1C, IQGAP1, UTRN, ACTR2, MYH9, NDRG1

Molecular

Function

cytoskeletal protein binding

5

CALD1, MSN, TPM1, ANXA2, ACTR2

ATP binding

6

MYH10, ACTR3, ACTG1, MYO1C, ACTR2, MYH9

nucleotide binding

7

MYH10, ACTR3, TUBA1B, ACTG1, MYO1C, ACTR2, MYH9

structural constituent of cytoskeleton

8

MSN, TPM1, ARPC4, ACTR3, TUBA1B, ACTG1, TLN1, ACTR2

identical protein binding

8

HSPB1, TPM1, TPM4, CTNNA1, ACTG1, FLNB, ANXA2, MYH9

RNA binding

9

HSPB1, FLNA, TMSB4X, ZYX, PFN1, CTNNA1, FLNB, ANXA2, MYH9

cadherin binding

10

CALD1, FLNA, PFN1, TAGLN2, CTNNA1, FLNB, TLN1, IQGAP1, MYH9, NDRG1

actin filament binding

16

TPM3, FLNA, MYH10, TPM1, ARPC4, ACTR3, TAGLN, TPM4, CTNNA1, FLNB, TLN1, MYO1C, IQGAP1, UTRN, ACTR2, MYH9

actin binding

19

CALD1, TPM3, FLNA, TMSB4X, PDLIM7, MSN, MYH10, TPM1, ARPC4, ACTR3, TAGLN, TPM4, PFN1, FLNB, TLN1, MYO1C, UTRN, ACTR2, MYH9

protein binding

33

CALD1, HSPB1, TPM3, FLNA, TMSB4X, PDLIM7, MSN, MYH10, DUSP23, TPM1, ARPC4, ACTR3, TAGLN, TUBA1B, KRT17, ZYX, TPM4, PFN1, TAGLN2, CTNNA1, MYL9, ACTG1, FLNB, TLN1, ANXA2, KRT7, MYO1C, IQGAP1, UTRN, ACTR2, MYH9, MYL6, NDRG1