Polymorphism | Group I (n = 70) n (%) | Group III (n = 200) n (%) | OR (95% CI) | P value |
TLR2 196_174 del |
| |||
ins/ins | 59 (84.3) | 152 (76) | Reference | |
ins/del | 10 (14.3) | 47 (23.5) | 0.548 (0.26 - 1.156) | 0.114 |
del/del | 1(1.4) | 1 (0.5) | 2.576 (0.159 - 41.8) | 0.506 |
TLR 4 Asp_299_Gly |
| |||
Asp/Asp | 64 (91.4) | 185 (92.5) | Reference | |
Asp/Gly | 6 (8.6) | 14 (7) | 1.239 (0.457 - 3.36) | 0.674 |
Gly/Gly | 0 (0) | 1 (0.5) | - | 1.000 |
Allele |
|
|
|
|
Asp | 134 (95.7) | 384 (96) | Reference | |
Gly | 6 (4.3) | 16 (4) | 1.075 (0.412 - 2.803) | 0.883 |
TLR 4 Thr_399_Ile |
| |||
Thr/Thr | 67 (95.7) | 193 (96.5) | Reference | |
Thr/Ile | 3 (4.3) | 7 (3.5) | 1.235 (0.31 - 4.91) | 0.765 |
Ile/Ile | 0 (0) | 0 (0) | - | 1.000 |
Allele Thr Ile |
|
| Reference | |
137 (97.9) | 393 (98.3) | 1.229 (0.319 - 4.821) | 0.767 | |
3 (2.1) | 7 (1.7) |
|
| |
Genotype |
|
|
|
|
AT | 130 (93) | 368 (92) | Reference | |
GT | 6 (4) | 23 (5.75) | 0.708 (0.194 - 2.587) | 0.601 |
AI | 4 (3) | 7 (1.75) | 1.887 (0.308 - 11.548) | 0.492 |
GI | 0 (0) | 2 (0.5) | - | 0.000 |