| Dose of epoetin at conversion | ||
Low (<420 IU/kg/month) (n = 30) | High (≥420 IU/kg/month) (n = 31) | Total (n = 61) | |
ESA dose (IU/kg/month), mean (SD) |
|
|
|
Darbepoetin alfa | 310.3 (79.0) | 641.8 (178.5) | 478.8 (216.5) |
Epoetin beta pegol |
|
|
|
At the time of switch | 390.7 (111.9) | 702.3 (245.3) | 549.0 (246.6) |
First month | 380.0 (142.9) | 650.8 (278.8) | 517.6 (259.6) |
Second month | 366.1 (195.5) | 649.3 (277.7) | 510.0 (278.2) |
Third month | 338.7 (244.4) | 638.4 (258.3) | 491.0 (291.7) |
ESA dose reduction (%), mean (SD) |
|
|
|
At the time of switch | 100.0 | 100.0 | 100.0 |
First month | 99.5 (40.6) | 90.7 (16.0) | 95.0 (30.7) |
Second month | 95.5 (46.9) | 90.8 (26.2) | 93.1 (37.6) |
Third month | 86.3 (58.5) | 90.7 (28.3) | 88.5 (45.4) |
ERI (IU/kg/month/g/dl), mean (SD) | |||
Darbepoetin alfa | 29.2 (7.6) | 62.3 (19.1) | 46.0 (22.1) |
Epoetin beta pegol |
|
|
|
At the time of a change | 36.5 (11.0) | 66.4 (25.0) | 51.7 (24.4) |
First month | 35.6 (14.7) | 61.2 (28.1) | 48.6 (25.8) |
Second month | 34.5 (19.7) | 61.7 (27.4) | 48.3 (27.4) |
Third month | 32.3 (25.7) | 60.0 (26.3) | 46.4 (29.3) |
ERI reduction (%), mean (SD) | |||
At the time of a change | 100.0 | 100.0 | 100.0 |
First month | 99.7 (44.9) | 89.9 (16.4) | 94.7 (33.7) |
Second month | 96.2 (50.1) | 91.1 (27.3) | 93.6 (39.9) |
Third month | 87.2 (61.6) | 90.3 (30.9) | 88.7 (48.1) |