| Perspective | Challenges | Source |
| Social | · Safety, fairness, social equality. | |
| · Public acceptance and trust. | | |
| · Privacy, transparency, and ethical use. | | |
| · liability and legal accountability. | | |
| Technology | · Technical integration, IT infrastructure, and lack of compatible systems. | |
| · Quality and functionality of AI systems. | | |
| · AI systems ownership and privatization. | | |
| · Data quality, management, and usability. | | |
| Organization | · Organization structure, size, culture, and management support. | |
| · Resistance to change and leadership roles. | | |
| · Health professional adoptions, required training programs, and fear of replacement. | | |
| · Patient awareness and AI explainability. | | |
| Regulatory | · AI regulations rapid change, uncertainty, and lack of clarity. | |
| · Approval process time and complexity. | | |
| · Compliance cost, resources, and expertise requirements. | | |
| · lack of consensus among international regulatory bodies. | | |
| Economic | · Limited financial resources. | |
| · Unclear Return on Investment (ROI). | | |
| · High development and maintenance costs. | | |
| · Reimbursement for AI based services. | |