| Factors affecting the risk of bleeding in patients with AF receiving an oral anticoagulant [67] | Baseline risk factors for fatal bleeding during VTE treatment [68] |
| Intensity of anticoagulation | Age > 75 years |
| Age | Metastatic cancer |
| History of stroke | Immobility ≥ 4 days |
| Previous bleeding | Major bleeding event within the past 30 days |
| Anaemia | Abnormal prothrombin time |
| Co-morbidities (e.g. hypertension, renal insufficiency, hepatic disease) | Platelet count < 100 × 109/l |
| Co-medications (e.g. antiplatelets, NSAIDs) | CrCl < 30 ml/min |
| Lifestyle (e.g. alcohol consumption) | Anaemia |