(n = 257) | 1 | 10 | (12.5) | 25 | (24.0) | 14 | (19.2) |
|
| 2 | 21 | (26.3) | 29 | (27.9) | 17 | (23.3) |
|
| 3 | 30 | (37.5) | 27 | (26.0) | 26 | (35.6) |
|
| 4 | 12 | (15.0) | 13 | (12.5) | 6 | (8.2) |
|
Headache | 0 | 43 | (53.8) | 52 | (50.5) | 38 | (51.4) | 0.365 |
(n = 257) | 1 | 12 | (15.0) | 27 | (26.2) | 12 | (16.2) |
|
| 2 | 13 | (16.3) | 14 | (13.6) | 8 | (10.8) |
|
| 3 | 11 | (13.8) | 9 | (8.7) | 15 | (20.3) |
|
| 4 | 1 | (1.3) | 1 | (1.0) | 1 | (1.4) |
|
Backache | 0 | 17 | (21.3) | 36 | (34.3) | 25 | (33.3) | 0.320 |
(n = 260) | 1 | 15 | (18.8) | 11 | (10.5) | 9 | (12.0) |
|
| 2 | 18 | (22.5) | 29 | (27.6) | 15 | (20.0) |
|
| 3 | 21 | (26.3) | 20 | (19.0) | 21 | (28.0) |
|
| 4 | 9 | (11.3) | 9 | (8.6) | 5 | (6.7) |
|
Constipation | 0 | 49 | (61.3) | 55 | (52.9) | 37 | (49.3) | 0.602 |
(n = 259) | 1 | 15 | (18.8) | 22 | (21.2) | 14 | (18.7) |
|
| 2 | 13 | (16.3) | 20 | (19.2) | 18 | (24.0) |
|
| 3 | 2 | (2.5) | 3 | (2.9) | 5 | (6.7) |
|
| 4 | 1 | (1.3) | 4 | (3.8) | 1 | (1.3) |
|
Diarrhea | 0 | 47 | (59.5) | 56 | (53.3) | 38 | (50.7) | 0.462 |
(n = 259) | 1 | 13 | (16.5) | 26 | (24.8) | 14 | (18.7) |
|
| 2 | 12 | (15.2) | 19 | (18.1) | 13 | (17.3) |
|
| 3 | 5 | (6.3) | 3 | (2.9) | 8 | (10.7) |
|
| 4 | 2 | (2.5) | 1 | (1.0) | 2 | (2.7) |
|
Abdominal distension | 0 | 29 | (36.3) | 40 | (38.1) | 28 | (37.8) | 0.427 |
(n = 259) | 1 | 22 | (27.5) | 26 | (24.8) | 17 | (23.0) |
|
| 2 | 22 | (27.5) | 32 | (30.5) | 16 | (21.6) |
|
| 3 | 6 | (7.5) | 4 | (3.8) | 10 | (13.5) |
|
| 4 | 1 | (1.3) | 3 | (2.9) | 3 | (4.1) |
|
Nausea | 0 | 68 | (85.0) | 86 | (81.9) | 60 | (81.1) | 0.568 |
(n = 259) | 1 | 6 | (7.5) | 8 | (7.6) | 5 | (6.8) |
|
| 2 | 5 | (6.3) | 5 | (4.8) | 2 | (2.7) |
|
| 3 | 0 | (0.0) | 4 | (3.8) | 5 | (6.8) |
|
| 4 | 1 | (1.3) | 2 | (1.9) | 2 | (2.7) |
|
Edema | 0 | 35 | (43.8) | 41 | (39.0) | 34 | (45.9) | 0.803 |
(n = 259) | 1 | 21 | (26.3) | 34 | (34.0) | 17 | (23.0) |
|
| 2 | 18 | (22.5) | 25 | (23.8) | 15 | (20.3) |
|
| 3 | 5 | (6.3) | 4 | (3.8) | 7 | (9.5) |
|
| 4 | 1 | (1.3) | 1 | (1.0) | 1 | (1.4) |
|