Patients’ characteristics

Total

(n. = 121)

<500

(n. = 23)

≥500

(n. = 98)

p-Value

<350

(n. = 10)

≥350

(n. = 111)

p-Value

Age: <10 years

≥10 years

88

33

19 (21.60%)

4 (12.12%)

69 (78.40%)

29 (87.88%)

0.24

8 (9.10%)

2 (6.06%)

80 (90.90%)

31 (93.94%)

0.73

Sex Male

Female

70

51

15 (21.43%)

8 (15.69%)

55 (78.57%)

43 (84.31%)

0.43

6 (8.37%)

4 (7.84%)

64 (91.43%)

47 (92.16%)

1.0

TLC <50,000 cells/μl

≥50,000 cells/μl

83

38

18 (21.69%)

5 (13.16%)

65 (78.31%)

33 (86.84%)

0.33

8 (9.64%)

2 (5.26%)

75 (90.36%)

36 (94.74%)

0.50

Mediastinal mass (119)*

Present

Absent

15

104

3 (20%)

19 (18.27%)

12 (80%)

85 (81.73%)

1.0

0

10 (9.62%)

15 (100%)

94 (90.38%)

0.36

Immunophenotyping

B-ALL

T-ALL

95

26

21 (22.11%)

2 (7.70%)

74 (78.89%)

24 (92.30%)

0.16

9 (9.5%)

1 (3.85%)

86 (90.5%)

25 (96.15%)

0.69

CNS involvement

Yes

No

7

114

1 (14.29%)

22 (19.30%)

6 (85.71%)

92 (80.70%)

1.0

1 (14.29%)

9 (7.89%)

6 (85.71%)

105 (92.11%)

0.46

Early response

RER

SER

106

15

21 (19.81%)

2 (13.33%)

85 (80.19%)

13 (86.67%)

0.74

8 (7.55%)

2 (13.33%)

98 (92.45%)

13 (86.67%)

0.36

Induction response

CR

not

104

17

20 (19.33%)

3 (17.65%)

84 (80.77%)

14 (82.35%)

1.0

8 (7.70%)

2 (11.76%)

96 (92.30%)

15 (88.24%)

0.63