| CTCs | ccfDNA |
Equipment | Need of specializad equipment | No need |
Isolation | Complex | Standard DNA preparation |
Whole Genome Amplication | Yes | No |
Heterogeneity | yes | Results represent an average |
Specific markers for isolation | Dependent | No dependent |
MTS | Ideal material | No |
Diagnosis and monitoring | Stablished by clinical studies | Clinical studies pending |