Method

Developer

Antibodies

Immunomagnetic assays: Positive Selection

Cell Search

Janssen Diagnostics

EpCAM-coated beads

Adna Test

AdnaGen (Langenhagen, Germany)

EpCAM, MUC-1 Mesothelin, molecular profiling

MACS Cell Separation technology

Miltenyi Bioteh (BergischGLadbach, Germany)

EpCAM, pan-CK

Dynabeads

Life Technologies

Monoclonal antibody BerEP4

Cell Collector

Gilupi

Medical wire anti-EpCAM coated placed into the patient vein blood steam for 30 minutes.

Biofluidic CTC Detection System

Biofluidica

EpCAM coated Chip

Immunomagnetic assays: Negative Selection

CTC-Chip

CTC-iChip

Daniel Haber and Mehmer Toner at Dana-Farber and Massachusetts General Hospital

EpCAM and CD45/citokeratin substraction

Based on CTCs biological and molecular features

Size

Size and deformability

Density

Physical properties

Others