Method | Developer | Antibodies |
Immunomagnetic assays: Positive Selection | ||
Cell Search | Janssen Diagnostics | EpCAM-coated beads |
Adna Test | AdnaGen (Langenhagen, Germany) | EpCAM, MUC-1 Mesothelin, molecular profiling |
MACS Cell Separation technology | Miltenyi Bioteh (BergischGLadbach, Germany) | EpCAM, pan-CK |
Dynabeads | Life Technologies | Monoclonal antibody BerEP4 |
Cell Collector | Gilupi | Medical wire anti-EpCAM coated placed into the patient vein blood steam for 30 minutes. |
Biofluidic CTC Detection System | Biofluidica | EpCAM coated Chip |
Immunomagnetic assays: Negative Selection | ||
CTC-Chip CTC-iChip | Daniel Haber and Mehmer Toner at Dana-Farber and Massachusetts General Hospital | EpCAM and CD45/citokeratin substraction |
Based on CTCs biological and molecular features | ||
Size | ||
Size and deformability | ||
Density | ||
Physical properties | ||
Others |