n

In-hospital mortality, n (%)

p

Postoperative complications, n (%)

p

All

3255

19

(0.6)

282

(8.7)

Tumor localization

Limb

3116

18

(0.6)

0.830

256

(8.2)

<0.001

Pelvis

139

1

(0.7)

26

(18.7)

Age (years)

≤59

1400

6

(0.4)

0.071

124

(8.9)

0.462

60 - 69

749

3

(0.4)

62

(8.3)

70 - 79

713

4

(0.6)

55

(7.7)

≥80

393

6

(1.5)

41

(10.4)

Sex

Male

1740

13

(0.7)

0.190

156

(9.0)

0.512

Female

1515

6

(0.4)

126

(8.3)

Tumor origin

Bone

330

6

(1.8)

0.009

61

(18.5)

<0.001

Soft tissue

2925

13

(0.4)

221

(7.6)

Prosthetic joint replacement

No

3151

18

(0.6)

0.461

257

(8.2)

<0.001

Yes

104

1

(2.8)

25

(24.0)

Free vascularized multi-tissue graft

No

3218

19

(0.6)

1.000

274

(8.5)

0.012

Yes

37

0

(0.0)

8

(21.6)

Preoperative vascular embolization

No

3219

18

(0.6)

0.191

271

(8.4)

<0.001

Yes

36

1

(2.8)

11

(30.6)

Distant metastasis

No

3137

16

(0.5)

0.004

261

(8.3)

<0.001

Yes

118

3

(2.5)

21

(17.8)

Blood transfusion (ml)

0

2750

7

(0.3)

<0.001

178

(6.5)

<0.001

1 - 999

128

5

(1.6)

51

(16.3)

1000 - 2499

184

3

(2.2)

28

(20.4)

≥2500

76

4

(7.1)

25

(44.6)

Hemodialysis

No

3235

16

(0.5)

<0.001

278

(8.6)

0.071

Yes

20

3

(15.0)

4

(20.0)

Diabetes mellitus

No

3007

16

(0.5)

0.178

250

(8.3)

0.014

Yes

248

3

(1.2)

32

(12.9)

Chemotherapy

No

2964

16

(0.5)

0.294

229

(7.7)

<0.001

Yes

291

3

(1.0)

53

(18.2)

Duration of anesthesia (min)

1 - 119

511

2

(0.4)

0.294

17

(3.3)

<0.001

120 - 239

1420

4

(0.3)

62

(4.4)