| Sl No | Vaccine/Antigen | Pathogen/Disease | Crop | Transformation method | Reference | Remarks |
| Viral | ||||||
| 1 | Norwalk virus capsid protein | Norwalk virus causing Gasteroenteritis | Tobacco leaves, Potato tubers | A. tumefaciens | [51] | Immunogenic in humans and mice |
| 2 | Respiratory Syncytial viral G and F protein | Respiratory Syncytial virus | Alfalfa mosaic virus display in Tobacco | Viral vector | [52] |
|
| 3 | Rotavirus VP6 protein | E. coli, rotavirus and Vibrio chlolerae | Potato tubers | A. tumefaciens | [53] | Immunogenic in mice |
| 4 | Recombinant vaccinia virus B5 | Smallpox | Tobacco and Collard | Agroinfiltration | [54] |
|
| 5 | Rabies virus glycoprotein and nucleo protein | Rabies | Viral vectors in Spinach leaves | Plant virus (TMV)-based expression system | [55] | Immunogenic in mice and humans |
| Maize (Zea mays) | Biolistic | [56] | Immunogenic in mice | |||
| Viral vectors in tobacco leaves | Agroinfiltration | [57] |
| |||
| 6 | Hepatitis B surface antigen | Hepatitis B | Lettuce | A. tumefaciens | [58] |
|
| Tomato | A. tumefaciens | [59] |
| |||
| Maize | A. tumefaciens | [60] |
| |||
| 7 | Dengue virus glycoprotein | Dengue | Tobacco | A. tumefaciens | [61] |
|
| 8 | Ebola immune complex | Ebola virus | Nicotiana benthamiana | Gemini viral vector | [62] | Immunogenic I mice |
| 9 | Monoclonal Antibody cocktail Zmapp | Ebola (2014) | Tobacco |
| Mapp Biopharmaceutical, 2014 | Administered in 2 patients |
| 10 | Influenza vaccine | Influenza | Tobacco |
| Medicago Inc, 2018 | Clinical trials |
| 11 | SARS-CoV-2 S protein | COVID-19 | N. benthamiana | Viral vectors | Medicago Inc., 2020 | Clinical trials |
| Bacterial | ||||||
| 1 | Cholera toxin B subunit protein | Cholera | Potato | A. tumefaciens | [63] | Immunogenic in mice |
| Tomato | A. tumefaciens | [24] |
| |||
| Rice (MucoRice-CTB/Q) | A. tumefaciens | [64] |
| |||
| 2 | E. coli heat-labile toxin B subunit | Escherichia coli | Potato tubers | A. tumefaciens | [65] | Immunogenic in mice |
| Maize seeds | A. tumefaciens | [66] |
| |||
| Carrots | A. tumefaciens | [22] | Immunoprotective in mice | |||
| 3 | Pseudomonas aeruginosa membrane protein F epitope | Pseudomonas aeruginosa | Cowpea mosaic virus epitope display in cowpea | Plant virus-mediated | [67] | Immunogenic in mice |
| Tobacco mosaic virus epitope display in tobacco | ||||||