| Diagnostic Category | Risk of Malignancy if NIFTP Not Cancer | Risk of Malignancy if NIFTP Equals Cancer | Usual Management |
| Non-diagnostic or unsatisfactory | 5% to 10% | 5% to 10% | Repeat FNA with ultrasound guidance |
| Benign | 0% to 3% | 0% to 3% | Clinical and sonographic follow-up |
| Atypia of undetermined significance or follicular lesion of undetermined significance | 6% to 18% | 10% to 30% | Repeat FNA, molecular testing, or lobectomy |
| Follicular neoplasm or suspicious for a follicular neoplasm | 10% to 40% | 25% to 40% | Molecular testing, or lobectomy |
| Suspicious for malignancy | 45% to 60% | 50% to 75% | Near-total thyroidectomy or lobectomy |
| Malignant | 94% to 96% | 97% to 99% | Near-total thyroidectomy or lobectomy |