Descriptive data

14*

1) Give characteristics of study participants (e.g. demographic, clinical, social) and information on exposures and potential confounders

NA

2) Indicate number of participants with missing data for each variable of interest

NA

Outcome data

15*

Report numbers of outcome events or summary measures

6

Main results

16

1) Give unadjusted estimates and, if applicable, confounder-adjusted estimates and their precision (e.g., 95% confidence interval). Make clear which confounders were adjusted for and why they were included

12

2) Report category boundaries when continuous variables were categorized

12

3) If relevant, consider translating estimates of relative risk into absolute risk for a meaningful time period

12

Other analyses

17

Report other analyses done—e.g. analyses of subgroups and interactions, and sensitivity analyses

12

Discussion

Key results

18

Summarise key results with reference to study objectives

7

Limitations

19

Discuss limitations of the study, taking into account sources of potential bias or imprecision. Discuss both direction and magnitude of any potential bias

7

Interpretation

20

Give a cautious overall interpretation of results considering objectives, limitations, multiplicity of analyses, results from similar studies, and other relevant evidence

7

Generalizability

21

Discuss the generalizability (external validity) of the study results

NA

Other information

Funding

22

Give the source of funding and the role of the funders for the present study and, if applicable, for the original study on which the present article is based

9