Parameter

Non-malignant

Group 3 = HCC

(N = 20)

Kruskal Wallis (P value)

Group 1 = Uncomplicated HCV (N = 20)

Group 2 = HCV + Cirrhosis (N = 20)

Age

Median

(min-max)

41^c

(25 - 52)

50

(39 - 55)

50^a

(35 - 85)

0.037^*

Sex

Male

Female

8 (40%)

12 (60%)

17 (85%)

3 (15%)

20 (100%)

0

0.001^{^}

WBCS count (10³/mm³)

Median

(min-max)

4.55

(3.5 - 8.16)

4.1^c

(3 - 4.5)

5.7^b

(3.1 - 15.52)

0.008^*

Hemoglobin level (g/dl)

Median

(min-max)

12.5^b

(11.2 - 14.7)

9.2^{a, c}

(9 - 10)

11.2^b

(6.7 - 15.6)

0.001^*

Platelet count (10³/mm³)

Median

(min-max)

215^{b, c}

(142 - 242)

110^a

(52 - 120)

92^a

(75 - 391)

0.004^*

Creatinine (mg/dl)

Median

(min-max)

0.7^{b, c}

(0.6 - 1)

1.1^a

(1 - 1.7)

1.5^a

(0.6 - 9)

0.001^*

INR

Median

(min-max)

1.04^{b, c}

(1 - 1.08)

1.5^a

(1.08 - 2)

1.4^a

(1.28 - 2.31)

<0.001^*

Total bilirubin (mg/dl)

Median

(min-max)

0.5^{b, c}

(0.4 - 1.1)

1.9^a

(1.2 - 3.5)

2.1^a

(0.6 -6.2)

0.001^*

Alkaline phosphatase (IU/L)

Median

(min-max)

61^{b, c}

(42 - 132)

134^a

(98 - 172)

127^a

(113 - 413)

0.001^*

ALT (IU/L)

Median

(min-max)

41^b

(20 - 79)

92^{a, c}

(80 - 121)

50^b

(19 - 160)

0.002^*

AST (IU/L)

Median

(min-max)

47.5^c

(23 - 86)

96

(80 - 154)

119^a

(28 - 740)

0.001^*

Albumin (g/dl)

Median

(min-max)

4.2^c

(3.6 - 4.5)

3.1^c

(2.6 - 3.2)

2.5^{a, b}

(2.2 - 2.5)

<0.001^*

Prothrombin activity %

Median

(min-max)

85^{b, c}

(82 - 100)

62^a

(43 - 72)

55.5^a

(29 - 63.1)

<0.001^*

HCV RNA level (IU/ml)

Median

(min-max)

2.04 × 10⁶

(14383 - 6.69×10⁷)

1.34 × 10⁶

(1.22x10⁵- 2.54 × 10⁶)

2.59 × 10⁶

(2.94 × 10⁵ - 1.45 × 10⁷)

0.244