Type/Preparation Conc.

Loaded amount^*

Drug loading (%)

Yield (%)

EE (%)

PLGA

0.25 mg/ml

1.2 ± 0.03

0.12 ± 0.004

39.76 ± 4.56

47.76 ± 1.6

0.5 mg/ml

2.06 ± 0.08

0.21 ± 0.008

31.66 ± 4.04

41.28 ± 1.6

1 mg/ml

4.52 ± 0.43

0.45 ± 0.044

56.33 ± 11.15

45.26 ± 4.4

1.5 mg/ml

5.58 ± 0.24

0.56 ± 0.025

64.88 ± 8.13

37.25 ± 1.6

PLGA-PEG

0.25 mg/ml

2.405 ± 0.081

0.240 ± 0.008

78.1 ± 0.6

96.1 ± 3.2

0.5 mg/ml

3.512 ± 0.030

0.3512 ± 0.031

84.5 ± 7.1

70.2 ± 6.1

1 mg/ml

6.229 ± 0.082

0.623 ± 0.008

56.2 ± 12.3

62.3 ± 0.8

1.5 mg/ml

8.890 ± 0.101

0.889 ± 0.010

85.7 ± 3.6

59.3 ± 0.7