Settings | Days | Control | 1000 mg/Kg∙BW | 3000 mg/Kg∙BW | 5000 mg/Kg∙BW |
Conjugated bilirubin (mg/l) | D0 D14 | 0.39 ± 0.02 0.41 ± 0.02 | 0.52 ± 0.05 0.51 ± 0.03 | 0.51 ± 0.03 0.56 ± 0.04 | 0.53 ± 0.04 0.64 ± 0.04 |
Total bilirubin (mg/l) | D0 D14 | 2.37 ± 0.15 2.09 ± 0.13 | 2.93 ± 0.25 3.15 ± 0.22 | 2.07 ± 0.08 4.23 ± 0.35** | 2.81 ± 0.02 4.12 ± 0.04** |
Creat (mg/l) | D0 D14 | 6.90 ± 0.22 7.05 ± 0.13 | 6.80 ± 0.28 7.09 ± 0.15 | 7.22 ± 0.18 8.05 ± 0.62 | 7.22 ± 0.25 8.97 ± 0.82 |
Uremia (g/l) | D0 D14 | 0.28 ± 0.03 0.41 ± 0.03 | 0.28 ± 0.02 0.33 ± 0.03 | 0.40 ± 0.04 0.45 ± 0.04 | 0.34 ± 0.06 0.42 ± 0.06* |
Uricemia (mg/l) | D0 D14 | 50.74 ± 3.03 50.11 ± 2.51 | 52.23 ± 1.9 50.16 ± 1.93 | 50.22 ± 3.05 59.54 ± 2.2* | 51.39 ± 0.83 58.04 ± 1.91** |
AST (UI/L) | D0 D14 | 32.77 ± 3.38 33.3 ± 2.61 | 37.21 ± 3.67 47.77 ± 2.25 | 38.54 ± 2.05 41.82 ± 3.55 | 41.25 ± 2.98 48.95 ± 3.25 |
ALT (UI/L) | D0 D14 | 79.14 ± 3.17 76.85 ± 2.02 | 91.36 ± 3.41 109.26 ± 8.67 | 95.06 ± 3.95 112.22 ± 5.98 | 91.95 ± 3.71 110.05 ± 1.5* |
ALP (UI/L) | D0 D14 | 43.97 ± 3.84 45.13 ± 6.13 | 51.68 ± 2.45 56.85 ± 3.38 | 43.97 ± 1.38 55.67 ± 3.472* | 49.34 ± 2.24 59.08 ± 1.76* |