| Parameters | Mean on D0 | Mean on D14 | P value | Difference |
| Weight of rats (g) | 143 ± 7 | 157 ± 9 | 0.4 | not significant |
| Creatinine (mg/L) | 13.7 ± 0.9 | 8.6 ± 0.4 | 0.1 | not significant |
| Transaminase AST (U/L) | 170 ± 12 | 147 ± 9 | 0.4 | not significant |
| Transaminase ALT (U/L) | 104 ± 6 | 99.0 ± 6 | 0.7 | not significant |
| Number of blood leukocytes (G/L) | 12.6 ± 0.7 | 13.0 ± 0.5 | 0.9 | not significant |
| Hemoglobin level (g/dl) | 15.3 ± 0.7 | 14.6 ± 0.4 | 0.7 | not significant |
| Number of blood platelets (G/L) | 496 ± 23 | 668 ± 17 | 0.1 | not significant |