KRAS

NRAS

No mutation

Mutation

P-value

No Mutation

Mutation

P-value

N

%

N

%

N

%

N

%

Age

Less than 60

5

83.3%

1

16.7%

0.039

4

66.7%

2

33.3%

0.551

More than 60

3

30.0%

7

70.0%

8

80.0%

2

20.0%

Gender

Male

7

70.0%

3

30.0%

0.039

7

70.0%

3

30.0%

0.551

Female

1

16.7%

5

83.3%

5

83.3%

1

16.7%

Tumor Size

Less than 5

2

28.6%

5

71.4%

0.614

7

100.0%

0

0.0%

0.383

More than 5

6

66.7%

3

33.3%

5

55.6%

4

44.4%

Tumor Site

Proximal Colon

4

36.4%

7

63.6%

0.106

8

72.7%

3

27.3%

0.755

Distal/Rectum

4

80.0%

1

20.0%

4

80.0%

1

20.0%

Tumor Grade

Well Differentiated

3

100.0%

0

0.0%

0.014

1

33.3%

2

66.7%

0.173

Moderately Differentiated

5

62.5%

3

37.5%

7

87.5%

1

12.5%

Poorly Differentiated

0

0.0%

5

100.0%

4

80.0%

1

20.0%

Depth of Invasion (pT)

T1 - T2

4

57.1%

3

42.9%

0.614

6

85.7%

1

14.3%

0.383

T3 - T4

4

44.4%

5

55.6%

6

66.7%

3

33.3%

Lymph Node Involvement (nT)

Negative

7

63.6%

4

36.4%

0.106

8

72.7%

3

27.3%

0.755

Positive

1

20.0%

4

80.0%

4

80.0%

1

20.0%

Distant

Metastasis (pM)

No metastasis

6

46.2%

7

53.8%

0.522

11

84.6%

2

15.4%

0.064

Metastasis

2

66.7%

1

33.3%

1

33.3%

2

66.7%

TNM

Stage 1 - 2

6

75.0%

2

25.0%

0.317

6

75.0%

2

25.0%

0.248

Stage 3 - 4

2

25.0%

6

75.0%

6

75.0%

2

25.0%

Mucinous Histology

No

7

77.8%

2

22.2%

0.012

6

66.7%

3

33.3%

0.383

Yes

1

14.3%

6

85.7%

6

85.7%

1

14.3%

LVI

Absent

7

53.8%

6

46.2%

0.522

10

76.9%

3

23.1%

0.712

Present

1

33.3%

2

66.7%

2

66.7%

1

33.3%

Alive

8

66.7%

4

33.3%

9

75.0%

3

25.0%