Pharmacokinetic parameters

Intravenous injection at a dose

Oral administration at doses

4.3 mg/kg

4.3 mg/kg

17.0 mg/kg

AUC (mg∙h/L)

18.1 ± 1.5

14.2 ± 1.3

59.4 ± 6.1

f_a (%)

100.0

77.8

82.0