| Parameters Skin Manifestations | Stage III n = 11 (15.94%) | Stage IV n = 20 (28.98%) | Stage V n = 38 (55.07%) |
| Pallor | 07 (63.63) | 16 (80.0) | 36 (94.73) |
| Xerosis | 03 (27.27) | 07 (35.0) | 10 (26.31) |
| Pruritus | 05 (45.45) | 15 (75) | 37 (97.36) |
| Pigmentation | 04 (36.36) | 14 (70) | 33 (86.84) |
| Purpura/Ecchymosis |
| 01 (5) | 04 (10.5) |
| Bacterial infection | 01 (9.09) |
| 03 (7.89) |
| Fungal infection | 01 (9.09) | 03 (15) | 07 (18.42) |
| Ulcerative stomatitis | 01 (9.09) |
| 03 (7.89) |
| Half-and-half nails | 03 (27.27) | 09 (45) | 15 (39.47) |