Primary tumor inhibition

Lung metastasis

Spleen weight g

Weight gain (−loss) g

Overall behavior in 3wk

Skin hair irritation

IV-PBS

No

13 (5)

0.62 (5)

2.6

normal

No

IV-Dox

Yes 44%

6 (5)

0.37 (5)

−1

normal

No

STID100

Yes 68%

1(5)

0.15 (5)

2.1

normal

Mostly no^*