Associated Protein, mRNAs or miR

Findings

Effects

miR-26b

mice with CLP

affected the antiviral response of the host

miR-27a

in the lungs of septic mice

up regulated in the progression to shock

miR-34a

in murine sepsis

Regulate vascular endothelial cell senescence

miR-106a/b

in whole blood of mice

Promote phagocytosis of macrophages by targeting SIRPa [41]

miR-126

in murine sepsis

Attenuates the increase in plasma levels of cytokines and

chemokines induced by sepsis

NADPH oxidase

patients with diagnosis of septic shock

Improve dysfunction of heart and papillary muscles in

patients with sepsis [42]

miR-223

in CLP mice

play an important role in MSC-induced cardioprotection in sepsis [43]

MFG-E8

rats by CLP

Reduce the level of inflammatory cytokines and increase the survival rate of experimental animals [44]

ADMSC

patients with diagnosis of septic shock

Improve dysfunction of heart and papillary muscles in patientswith sepsis [45]