Associated Protein, mRNAs or miR | Findings | Effects |
miR-15a | Differentially expressed in adult a neonatal sepsis | Inhibits angiogenesis through direct targeting of VEGF and FGF [33] |
miR-16a | in mice exposed to lipopolysaccharides | expression was shown to be up-regulated Following CLP [34] |
miR-17 | in the whole blood of mice after CLP | were significantly up-regulated in the microarray analysis in mice subcutaneously [35] |
miR-20a/b | in the whole blood of mice after CLP | were significantly up-regulated in the microarray analysis in mice subcutaneously [35] |
miR-21 | in late sepsis of mice | with higher mortality in LPS-peritonitis model [36] |
miR-146a | patients with severe sepsi | Predicted mortality and treatment outcomes induced by severe sepsis and sepsis. |
miR-150 | in septic patients | associated with survival rate in patients with sepsis [37] |
miR-195 | mice with CLP | only significantly expressed in the CLP model |
miR-223 | patients with mild sepsis severe sepsis and septic shock | as novel diagnostic biomarkers of sepsis [38] |
ATF3 | mice | an interesting sepsis-AKI biomarker [39] |
SPTLC3 | sepsis patient | potential classifier to monitor clinical progression of sepsis [40] |