Associated Protein, mRNAs or miR

Findings

Effects

miR-15a

Differentially expressed in adult a neonatal sepsis

Inhibits angiogenesis through direct targeting of VEGF and FGF [33]

miR-16a

in mice exposed to lipopolysaccharides

expression was shown to be up-regulated Following CLP [34]

miR-17

in the whole blood of mice after CLP

were significantly up-regulated in the microarray analysis in mice subcutaneously [35]

miR-20a/b

in the whole blood of mice after CLP

were significantly up-regulated in the microarray analysis in mice subcutaneously [35]

miR-21

in late sepsis of mice

with higher mortality in LPS-peritonitis model [36]

miR-146a

patients with severe sepsi

Predicted mortality and treatment outcomes induced

by severe sepsis and sepsis.

miR-150

in septic patients

associated with survival rate in patients with sepsis [37]

miR-195

mice with CLP

only significantly expressed

in the CLP model

miR-223

patients with mild sepsis severe sepsis and septic shock

as novel diagnostic biomarkers of sepsis [38]

ATF3

mice

an interesting sepsis-AKI biomarker [39]

SPTLC3

sepsis patient

potential classifier to monitor clinical progression of sepsis [40]