Variables | Total cohort | ||||
Total | HU (UA ≥ 7.1 mg/dL) | Non HU (UA < 7.1 mg/dL) | P-value | Standardized Differences | |
n = 122 | n = 20 | n = 102 | |||
Clinical Findings |
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Age (years) | 58.7 ± 13.9 | 59.8 ± 14.0 | 58.4 ± 13.9 | 0.7 | 0.100 |
Gender (Male; % ) | 39.3 | 70.0 | 33.3 | 0.002 | 0.790 |
SBP (mmHg) | 124.9 ± 8.1 | 130.0 ± 7.8 | 123.9 ± 7.8 | 0.002 | 0.782 |
DBP (mmHg) | 76.4 ± 6.2 | 80.5 ± 5.2 | 75.6 ± 6.1 | 0.001 | 0.865 |
MBP (mmHg) | 92.6 ± 6.6 | 97.0 ± 5.9 | 91.7 ± 6.4 | 0.0009 | 0.861 |
BMI (kg/m2) | 23.9 ± 4.1 | 25.5 ± 5.8 | 23.6 ± 3.7 | 0.06 | 0.391 |
Visceral fat area (cm2) | 117.1 ± 62.1 | 158.8 ± 75.4 | 108.9 ± 56.0 | 0.0008 | 0.751 |
Subcutaneous fat area (cm2) | 184.5 ± 94.3 | 212.4 ± 146.1 | 179.1 ± 80.3 | 0.1 | 0.282 |
IMT(mm) | 1.44 ± 0.81 | 1.75 ± 1.02 | 1.38 ± 0.76 | 0.1 | 0.411 |
Laboratory Findings |
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Serum Albumin (g/dL) | 4.2 ± 0.3 | 4.1 ± 0.4 | 4.2 ± 0.3 | 0.1 | 0.283 |
Hemoglobin (g/dL) | 13.5 ± 1.5 | 12.9 ± 2.1 | 13.6 ± 1.4 | 0.1 | 0.392 |
eGFR (mL/min/1.73 m2) | 63.7 ± 19.8 | 43.8 ± 19.0 | 67.6 ± 17.6 | <0.0001 | 1.300 |
Uric Acid (mg/dL) | 5.5 ± 1.5 | 7.8 ± 0.6 | 5.0 ± 1.2 | <0.0001 | 2.951 |
Total Cholesterol (mg/dL) | 211.9 ± 49.3 | 213.4 ± 46.7 | 211.6 ± 50.0 | 0.9 | 0.037 |
LDL Cholesterol (mg/dL) | 124.4 ± 44.7 | 131.0 ± 34.5 | 123.1 ± 46.5 | 0.5 | 0.193 |
HDL Cholesterol (mg/dL) | 59.2 ± 16.9 | 51.3 ± 15.5 | 60.7 ± 16.8 | 0.02 | 0.582 |
Triglyceride (mg/dL) | 141.2 ± 71.4 | 155.7 ± 64.5 | 138.3 ± 72.6 | 0.3 | 0.253 |
UACR (mg/g Cre) | 238.7 ± 548.1 | 649.7 ± 1035.8 | 158.1 ± 343.6 | 0.0002 | 0.637 |
Concomitant drugs |
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Antihypertensive agents (%) | 61.5 | 70.0 | 59.8 | 0.4 | 0.215 |
Antidyslipidemic agents (%) | 35.3 | 35.0 | 35.3 | 1.0 | 0.006 |
Antidiabetic agents (%) | 13.9 | 30.0 | 10.8 | 0.02 | 0.491 |
Corticosteroids (%) | 16.4 | 15.0 | 16.7 | 0.9 | 0.047 |
Immunosuppressing agents (%) | 5.7 | 5.0 | 5.9 | 0.9 | 0.040 |
Diuretics (%) | 15.6 | 20.0 | 14.7 | 0.6 | 0.140 |
Comorbidities |
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Hypertension (%) | 62.3 | 70.0 | 60.8 | 0.4 | 0.194 |
HU (UA ≥ 7.1 mg/dL) (%) | 16.4 | 100.0 | 0.0 | <0.0001 | - |
Hypercholesterolemia (%) | 59.8 | 55.0 | 60.8 | 0.6 | 0.118 |
Hypertriglyceridemia (%) | 63.9 | 65.0 | 63.7 | 0.9 | 0.027 |
Diabetes mellitus (%) | 21.3 | 35.0 | 18.6 | 0.1 | 0.377 |