Patient | AUC(0-t) | AUC(0-∞) | AUMC(0-∞) | MRT(0-∞) | VRT(0-∞) | t1/2z | Tmax | Vz | CLz | Cmax |
Group | mg/L*h | mg/L*h | h*h*mg/L | h | h2 | h | h | L | L/h | mg/L |
A | 49.15 ± 10.22 | 55.84 ± 13.16 | 205.17 ± 69.50 | 3.62 ± 0.45 | 9.05 ± 3.63 | 1.93 ± 0.50 | 1.25 ± 0.46 | 20.53 ± 6.49 | 7.44 ± 1.36 | 12.73 ± 1.65 |
B | 41.65 ± 5.40 | 46.73 ± 7.15 | 169.40 ± 36.70 | 3.60 ± 0.28 | 7.58 ± 1.71 | 1.72 ± 0.24 | 1.75 ± 0.46 | 21.43 ± 2.44 | 8.73 ± 1.27 | 9.70 ± 1.20 |
C | 25.12 ± 2.66 | 30.97 ± 3.21 | 142.20 ± 34.81 | 4.56 ± 0.90 | 14.45 ± 8.51 | 2.49 ± 0.76 | 2.13 ± 0.35 | 46.15 ± 12.89 | 13.06 ± 1.60 | 5.95 ± 0.63 |
D | 13.70 ± 1.02 | 18.07 ± 3.86 | 95.50 ± 52.52 | 5.00 ± 1.59 | 22.92 ± 20.10 | 3.05 ± 1.34 | 1.25 ± 0.46 | 93.97 ± 20.99 | 22.97 ± 4.55 | 3.37 ± 0.25 |