Characteristic

Univarible model

Initial multivariable model

Final multivariable model

HR¹

95% CI¹

p-value

HR¹

95% CI¹

p-value

HR¹

95% CI¹

p-value

Complete COVID-19 vaccination

No

—

—

—

—

—

—

Yes

0.27

0.11, 0.66

0.004

0.27

0.11, 0.66

0.004

0.27

0.11, 0.67

0.005

Age (Year)

<55

—

—

—

—

—

—

≥55

1.84

1.31, 2.59

<0.001

1.78

1.28, 2.49

<0.001

1.82

1.32, 2.52

<0.001

Sex

Female

—

—

—

—

—

—

Male

1.08

0.79, 1.47

0.6

1.05

0.78, 1.42

0.8

1.02

0.76, 1.38

0.9

Diabetes

No

—

—

—

—

—

—

Yes

1.55

1.12, 2.15

0.008

1.55

1.12, 2.14

0.008

1.60

1.17, 2.19

0.003

High blood pressure

No

—

—

—

—

Yes

1.20

0.87, 1.66

0.3

1.22

0.88, 1.68

0.2

Asthma

No

—

—

Yes

0.84

0.34, 2.05

0.7

HIV

No

—

—

—

—

Yes

1.46

0.79, 2.69

0.2

1.43

0.78, 2.63

0.2

Renal failure

No

—

—

—

—

—

—

Yes

3.78

1.64, 8.71

0.002

3.70

1.61, 8.49

0.002

3.94

1.73, 8.98

0.001

Pregnancy

No

—

—

Yes

1.47

0.82, 2.63

0.2

Cancer

No

—

—

Yes

0.76

0.11, 5.50

0.8

Hemoglobinopathy

No

—

—

Yes

2.04

0.64, 6.52

0.2

Obesity

No

—

—

Yes

1.16

0.47, 2.88

0.7