CRITERIA | POINTS |
Family history |
|
A first degree member with early cardiovascular disease (M < 55 years old; W < 60 years old) or a first degree member with LDL-C > 190 mg/dl | 1 |
A first degree member with tendon xanthomas or corneal arches or a child under 18 with LDLC > 135 mg/dl | 2 |
Personal history |
|
Patient with early coronary artery disease (M < 55 years old; F < 60 years old) | 2 |
Patient with early cerebral or peripheral vascular disease | 1 |
Examen Clinique |
|
Xanthomes tendineux | 6 |
Corneal arch before 45 | 4 |
LDL-C level (before any treatment) |
|
LDL-C ≥ 330 mg/dl | 8 |
LDL-C between 250 and 329 mg/dl | 5 |
LDL-C between 190 and 249mg/dl | 3 |
LDLC between 150 and 189 mg/dL | 1 |
TEST GENETIQUE |
|
Mutation on the LDL-R, APOB or PCSK-9 gene | 8 |