Genotype

HWE

p value

Allele

P value^b

rs460000

C/C^a

C/A^a

A/A^a

C^a

A^a

Patient

25

(27.8%)

48 (53.3%)

17 (18.9%)

p = 0.530

98 (54.4%)

82 (45.6%)

p = 0.357

Healthy subject

27 (23.7%)

60 (52.6%)

27 (23.7%)

p = 0.708

114

(50.0%)

114 (50.0%)

rs6347

A/A

A/G

G/G

A

G

Patient

67 (74.4%)

23 (25.6%)

0 (0.0%)

p = 0.346

157 (87.2%)

23 (12.8%)

p = 0.151

Healthy subject

98 (86.0%)

13 (11.4%)

3 (2.6%)

p = 0.027

209 (91.7%)

19 (8.3%)

rs2270912

C/C

C/T

T/T

C

T

Patient

83 (92.2%)

7 (7.8%)

0 (0.0%)

N/A^c

173 (96.1%)

7 (3.9%)

p = 0.0024

Healthy subject

114 (100%)

0 (0.0%)

0 (0.0%)

N/A^c

228 (100%)

0 (0.0%)

rs429699

G/G

G/A

A/A

G

A

Patient

35 (38.9%)

41 (45.6%)

1 (15.6%)

p = 0.823

111 (61.7%)

69

(38.3%)

p = 0.443

Healthy subject

48 (42.1%)

53 (46.5%)

13 (11.4%)

p = 0.839

149 (65.4%)

79 (34.6%)

rs28363130

A/A

A/G

G/G

A

G

Patient

82 (91.1%)

8 (8.9%)

0 (0.0%)

N/A^c

172 (95.6%)

8 (4.4%)

p = 0.0057

Healthy subject

113 (99.1%)

1 (0.9%)

0 (0.0%)

N/A^c

227 (99.6%)

1 (0.4%)