Compound number

Spectral1H NMR data

1a

δ 1.77 (s, CH3, 3H), 1.7 (s, CH3, 3H), 7.5 (q, 3H, Ar-H)

1b

δ 1.77 (s, CH3, 3H), 1.7 (s, CH3, 3H,), 7.2 - 7.5 (m, 4H, Ar-H)

1c

δ 1.9 (s, CH3, 3H), 1.77 (s, CH3, 3H), 6.9 (q, 3H, Ar-H),

1d

δ 1.9 (s, CH3, 3H), 1.77 (s, CH3, 3H), 7.4 (d, 2H, Ar-H)

1e

Δ 1.77 (s, CH3, 3H), 1.7 (s, CH3, 3H), 2.3 (m, CH2, 2H), 5.4 (m, CH, 4H), 3.98 (m, H, CH), 8.9 (s, H, Ar-H)

3a

δ (s, CH3, 3H), 1.7 (s, CH3, 3H), 7.5 (m, 3H, Ar-H), 3.4 (d, 2H, -CH2’’’’’’), 6.9 (d, 1H, -CH’), 2.4 (m, H, OH), 4.4 (m, 3H, CH’’’, CH’’’’, CH’’’’’)

3b

Δ 1.77 (s, CH3, 3H), 1.7 (s, CH3, 3H), 7.5 (m, 4H, Ar-H), 3.4 (d, 2H, -CH2’’’’’’), 6.9 (d, 1H, -CH’), 2.4 (m, H, OH), 4.4 (m, 3H, CH’’’, CH’’’’, CH’’’’’)

3c

Δ 1.77 (s, CH3, 3H), 1.7 (s, CH3, 3H), 7.5 (m, 4H, Ar-H), 3.4 (d, 2H, -CH2’’’’’’), 6.1 (d, 1H, -CH’), 3.4 (m, 4H, 4OH, 2H, NH2), 4.4 (m, 3H, CH’’’, CH’’’’, CH’’’’’)

3d

δ 1.77 (s, CH3, 3H), 1.7 (s, CH3, 3H), 6.7-7.5 (d, d, 2H, Ar-OH), 2.9 (m, H, 5OH), 6.1 (d, 1H, -CH’), 3.37 - 4.4 (m, 3H, CH’’’, CH’’’’, CH’’’’’)

3e

δ 1.77 (s, CH3, 3H), 1.7 (s, CH3, 3H), 7.5 (q, 3H, Ar-H), 7.2 (s, 2H, -CH2’’’’’’), 6.9 (d, 1H, -CH’’), 2.4 (m, H, OH), 4.4 (q, 4H, CH’, CH’’’, CH’’’’, CH’’’’’)