Polymorphism | Men | OR (95% CI) | p | Women | OR (95% CI) | p | ||
N0 n (%) | N1 - N3 n (%) | N0 n (%) | N1 - N3 n (%) | |||||
VEGF −634C > G | n = 87 | n = 79 |
| n = 35 | n = 17 |
| ||
GG | 45 (51.7) | 43 (54.4) | 1.00 | 0.82 | 16 (45.7) | 8 (47.1) | 1.00 | 0.99 |
GC | 33 (37.9) | 30 (38) | 0.95 (0.50 - 1.82) | 17 (48.6) | 8 (47.1) | 0.94 (0.29 - 3.11) | ||
CC | 9 (10.3) | 6 (7.6) | 0.70 (0.23 - 2.13) | 2 (5.7) | 1 (5.9) | 1.00 (0.08 - 12.76) | ||
GC+CC | 42 (48.3) | 36 (45.6) | 0.90 (0.49 - 1.65) | 0.73 | 19 (54.3) | 9 (52.9) | 0.95 (0.30 - 3.03) | 0.93 |
VEGF −2578C > A | n = 87 | n = 79 |
| n = 35 | n = 17 |
| ||
CC | 25 (28.7) | 25 (31.6) | 1.00 | 0.18 | 4 (11.4) | 8 (47.1) | 10.00 (1.44 - 69.26) |
|
CA | 40 (46) | 43 (54.4) | 1.07 (0.53 - 2.17) | 21 (60) | 7 (41.2) | 1.67 (0.29 - 9.52) | 0.02 | |
AA | 22 (25.3) | 11 (13.9) | 0.50 (0.20 - 1.24) | 10 (28.6) | 2 (11.8) | 1.00 |
| |
CA+ AA | 62 (71.3) | 54 (68.3) | 0.87 (0.45 - 1.69) | 0.68 | 31 (88.6) | 9 (52.9) | 0.14 (0.035 - 0.60) | 0.01 |
VEGF +936C > T | n = 87 | n = 79 |
| n = 35 | n = 17 |
| ||
CC | 60 (69) | 55 (69.6) | 1.00 | 0.77 | 22 (62.9) | 11 (64.7) | 1.00 | 0.39 |
CT | 23 (26.4) | 22 (27.9) | 1.04 (0.52 - 2.08) | 12 (34.3) | 4 (23.5) | 0.67 (0.17 - 2.55) | ||
TT | 4 (4.6) | 2 (2.5) | 0.55 (0.10 - 3.10) | 1 (2.9) | 2 (11.8) | 4.00 (0.33 - 49.08) | ||
CT + TT | 27 (31) | 24 (30.4) | 0.97 (0.50 - 1.88) | 0.93 | 13 (37.1) | 6 (35.3) | 0.92 (0.28 - 3.09) | 0.90 |