Polymorphism | Men | Women | ||||||||||||
Control n (%) | ADC n (%) | OR (95% CI) | p | SCC n (%) | OR (95% CI) | p | Control n (%) | ADC n (%) | OR (95% CI) | p | SCC n (%) | OR (95% CI) | p | |
VEGF −634C > G | n = 295 | n = 64 |
| n = 117 |
| n = 88 | n = 44 |
| n = 8 |
| ||||
GG | 150 (50.9) | 33 (51.6) | 1.00 | 0.23 | 61 (52.1) | 1.00 | 0.09 | 48 (54.5) | 18 (40.9) | 1.00 | 0.27 | 6 (75.0) | 1.00 | 0.24 |
GC | 133 (45.1) | 25 (39.1) | 0.85 (0.48 - 1.51) | 45 (38.5) | 0.83 (0.53 - 1.31) | 35 (3.8) | 24 (54.5) | 1.83 (0.86 - 3.87) | 1 (12.5) | 0.23 (0.03 - 1.98) | ||||
CC | 12 (4.1) | 6 (9.4) | 2.27 (0.80 - 6.49) | 11 (9.4) | 2.25 (0.94 - 5.38) | 5 (5.7) | 2 (4.5) | 1.07 (0.19 - 6.00) | 1 (12.5) | 1.60 (0.16 - 16.10) | ||||
GC + CC | 145 (49.1) | 31 (48.4) | 0.97 (0.57 - 1.67) | 0.92 | 56 (47.9) | 0.95 (0.62 - 1.46) | 0.81 | 40 (45.5) | 26 (59.1) | 1.73 (0.83 - 3.61) | 0.14 | 2 (2.05) | 0.40 (0.08 - 2.09) | 0.25 |
VEGF −2578C > A | n = 295 | n = 64 |
| n = 117 |
| n = 88 | n = 44 |
| n = 8 |
| ||||
CC | 65 (22.0) | 16 (25.0) | 1.59 (0.69 - 3.67) | 0.47 | 39 (33.3) | 1.00 |
| 21 (23.9) | 10 (22.7) | 1.37 (0.45 - 4.12) | 0.52 | 2 (25.0) | 0.55 (0.09 - 3.30) | 0.30 |
CA | 159 (53.9) | 37 (57.8) | 1.50 (0.72 - 3.11) | 50 (42.7) | 0.52 (0.32 - 0.87) | 0.05 | 44 (50.0) | 26 (59.1) | 1.70 (0.66 - 4.35) | 2 (25.0) | 0.26 (0.04 - 1.54) | |||
AA | 71 (24.1) | 11 (17.2) | 1.00 | 28 (23.9) | 0.66 (0.36 - 1.19) |
| 23 (26.1) | 8 (18.2) | 1.00 | 4 (50.0) | 1.00 | |||
CA+ AA | 230 (78.0) | 48 (75.0) | 0.85 (0.45 - 1.59) | 0.73 | 78 (66.7) | 0.57 (0.35 - 0.91) | 0.02 | 67 (76.1) | 34 (77.3) | 1.07 (0.45 - 2.52) | 0.88 | 6 (75.0) | 0.94 (0.17 - 5.02) | 0.94 |
VEGF +936C > T | n = 295 | n = 64 |
| n = 117 |
| n = 88 | n = 44 |
| n = 8 |
| ||||
CC | 217 (73.6) | 51 (79.7) | 1.00 | 0.56 | 74 (63.2) | 1.00 | 0.08 | 59 (67.0) | 28 (63.6) | 1.00 | 0.51 | 5 (62.5) | 1.00 | 0.20 |
CT | 70 (23.7) | 12 (18.8) | 0.73 (0.37 - 1.45) | 36 (30.8) | 1.51 (0.93 - 2.44) | 24 (27.3) | 15 (34.1) | 1.32 (0.60 - 2.89) | 1 (12.5) | 0.49 (0.05 - 4.43) | ||||
TT | 8 (2.7) | 1 (1.6) | 0.53 (0.07 - 4.35) | 0.56 | 7 (6.0) | 2.57 (0.90 - 7.32) | 5 (5.7) | 1 (2.3) | 0.42 (0.05 - 3.78) | 2 (25.0) | 4.72 (0.72 - 30.84) | |||
CT + TT | 78 (26.4) | 13 (20.3) | 0.71 (0.37 - 1.37) | 0.30 | 43 (36.8) | 1.62 (1.02 - 2.55) | 0.04 | 29 (33.0) | 16 (36.4) | 1.16 (0.54 - 2.48) | 0.70 | 3 (37.5) | 1.22 (0.27 - 5.46) | 0.80 |