Polymorphism

Men

Women

Control

n (%)

ADC

n (%)

OR

(95% CI)

p

SCC

n (%)

OR

(95% CI)

p

Control

n (%)

ADC

n (%)

OR

(95% CI)

p

SCC

n (%)

OR

(95% CI)

p

VEGF

−634C > G

n = 295

n = 64

n = 117

n = 88

n = 44

n = 8

GG

150

(50.9)

33 (51.6)

1.00

0.23

61 (52.1)

1.00

0.09

48 (54.5)

18 (40.9)

1.00

0.27

6

(75.0)

1.00

0.24

GC

133

(45.1)

25 (39.1)

0.85

(0.48 - 1.51)

45 (38.5)

0.83

(0.53 - 1.31)

35

(3.8)

24 (54.5)

1.83

(0.86 - 3.87)

1

(12.5)

0.23

(0.03 - 1.98)

CC

12

(4.1)

6

(9.4)

2.27

(0.80 - 6.49)

11 (9.4)

2.25

(0.94 - 5.38)

5

(5.7)

2

(4.5)

1.07

(0.19 - 6.00)

1

(12.5)

1.60

(0.16 - 16.10)

GC + CC

145

(49.1)

31 (48.4)

0.97

(0.57 - 1.67)

0.92

56 (47.9)

0.95

(0.62 - 1.46)

0.81

40 (45.5)

26 (59.1)

1.73

(0.83 - 3.61)

0.14

2

(2.05)

0.40

(0.08 - 2.09)

0.25

VEGF

−2578C > A

n = 295

n = 64

n = 117

n = 88

n = 44

n = 8

CC

65

(22.0)

16 (25.0)

1.59

(0.69 - 3.67)

0.47

39 (33.3)

1.00

21 (23.9)

10 (22.7)

1.37

(0.45 - 4.12)

0.52

2

(25.0)

0.55

(0.09 - 3.30)

0.30

CA

159

(53.9)

37 (57.8)

1.50

(0.72 - 3.11)

50 (42.7)

0.52

(0.32 - 0.87)

0.05

44 (50.0)

26 (59.1)

1.70

(0.66 - 4.35)

2

(25.0)

0.26

(0.04 - 1.54)

AA

71

(24.1)

11 (17.2)

1.00

28 (23.9)

0.66

(0.36 - 1.19)

23 (26.1)

8 (18.2)

1.00

4

(50.0)

1.00

CA+ AA

230 (78.0)

48 (75.0)

0.85

(0.45 - 1.59)

0.73

78 (66.7)

0.57

(0.35 - 0.91)

0.02

67 (76.1)

34 (77.3)

1.07

(0.45 - 2.52)

0.88

6 (75.0)

0.94

(0.17 - 5.02)

0.94

VEGF +936C > T

n = 295

n = 64

n = 117

n = 88

n = 44

n = 8

CC

217 (73.6)

51 (79.7)

1.00

0.56

74 (63.2)

1.00

0.08

59 (67.0)

28 (63.6)

1.00

0.51

5 (62.5)

1.00

0.20

CT

70

(23.7)

12 (18.8)

0.73

(0.37 - 1.45)

36 (30.8)

1.51

(0.93 - 2.44)

24 (27.3)

15 (34.1)

1.32

(0.60 - 2.89)

1

(12.5)

0.49

(0.05 - 4.43)

TT

8

(2.7)

1

(1.6)

0.53

(0.07 - 4.35)

0.56

7

(6.0)

2.57

(0.90 - 7.32)

5

(5.7)

1

(2.3)

0.42

(0.05 - 3.78)

2

(25.0)

4.72

(0.72 - 30.84)

CT + TT

78

(26.4)

13 (20.3)

0.71

(0.37 - 1.37)

0.30

43 (36.8)

1.62

(1.02 - 2.55)

0.04

29 (33.0)

16

(36.4)

1.16

(0.54 - 2.48)

0.70

3

(37.5)

1.22

(0.27 - 5.46)

0.80