n = 33

Progressive disease

20 (60.6%)

Adverse events

10 (30.3%)

Anorexia

5 (15.2%)

Nausea

1 (3.0%)

Diarrhea

1 (3.0%)

Neutropenia

1 (3.0%)

Alanine aminotransferase increased

1 (3.0%)

Creatinine increased

1 (3.0%)

Cognitive disturbance

2 (6.1%)

Ileus

1 (3.0%)