Baseline	6 Month	Change at 6 month	N (%)	Agreement Statistic	Symmetry of Disagreement
Baseline	6 Month	Change at 6 month	N (%)	Kappa Coefficient	Bowker’s Test
Negative	Negative	Negative to Negative	25 (20.3)	0.24, p = 0.0001	p = 0.0001
	Positive	Negative to Positive	38 (30.9)
Positive	Negative	Positive to Negative	3 (2.4)
	Positive	Positive to Positive	57 (46.3)