Baseline

6 Month

Change at 6 month

N (%)

Agreement Statistic

Symmetry of Disagreement

Kappa Coefficient

Bowker’s Test

Negative

Negative

Negative to Negative

25 (20.3)

0.24, p = 0.0001

p = 0.0001

Positive

Negative to Positive

38 (30.9)

Positive

Negative

Positive to Negative

3 (2.4)

Positive

Positive to Positive

57 (46.3)