| Rodent Type | Rodent Model | Research Application | References |
| Mice | ob/ob mouse | Obese mouse | Coleman [137] |
| Mice | db/db mouse | Diabetic mouse | Coleman [137] |
| Mice | s/s mouse | Genetically engineered animal model of leptin receptor deficiency | Bates et al., [138] |
| Rat | Leptin receptor-deficient rats | Leptin-resistant obesity | Bates et al., [138] |
| Rat | fa/fa-fatty rat | Extracellular domain of the leptin receptor obesity | Bray and York, [139] |
| Rat | Zucker Diabetic Fatty (ZDF) rats | Obesity | Zierath et al., [140] |
| Rat | Wistar Kyoto fatty rat (WDF rat) | Obesity and co-morbidities | Ikeda et al., [141] |
| Mouse | POMC knockout mouse | Deficit downstream of the brain leptin receptor | O’Rahilly [142] |
| Rat | Diet-induced obese (DIO) | Obesity | Levin and Dunn-Meynell [143] |
| Rat | Diet-resistant (DR) | Obesity | Levin and Dunn-Meynell [143] |
| Rat | Cafeteria diet-induced obesity (CD) | Obesity | Rogers and Blundell [144] |
| Rat | High-fat diet-induced obesity (HF) | Obesity | Willett and Leibel [145] |
| Mice | New Zealand obese mouse (NZO) | Obese ans type-2 diabetes | Joost [146] |
| Mice | Age-related obesity in mice (LOO) (C57B6) | Obesity | Becskei et al., [147] |
| Rat and Mice | Early postnatal overfeeding induced obesity; rearing in small litters | Obesity | Faust et al., [148] |
| Mice | Glucose transporter subtype 4 (GLUT4) | Obesity | Shepherd et al., [147] |
| Rat | GH-deficient dwarf rat | Deficient growth hormone (GH) | Davies et al., [150] |
| Rat | Diet-Induced obesity | Obesity | Hamda et al. [151] |
| Rat | Juvenile obesity animal model | Obesity | Sandra and Hamda [152] |