Included | Sano J., Ohki K., Higuchi T., Aihara K., Mizuno S., Kajimoto O., et al. | Effect of casein hydrolysate, prepared with protease derived from Aspergillus oryzae, on subjects with high-normal blood pressure or mild hypertension. | Journal of Medicinal Food. 2005; 8(4):423-430. | Medline/ Cochrane |
4 | Yamasue K., Morikawa N., Mizushima S. and Tochikubo O. | The blood pressure lowering effect of lactotripeptides and salt intake in 24-h ambulatory blood pressure measurements. | Clinical and Experimental Hypertension 2010; 32(4): 214-220. | Medline/ Cochrane |
7 | Yasuda K., Aihara K., Komazaki K., Mochii M. and Nakamura Y. | [Effect of large high intake of tablets containing “lactotripeptides (VPP, IPP)” on blood pressure, pulse rate and clinical parameters in healthy volunteers]. | Journal of Nutritional Food 2001; 4(3): 63-72. Japanese | J-DREAM III/ J-STAGE |
13 | Yoshizawa M., Maeda S., Miyaki A., Misono M., Choi Y., Shimojo N., Ajisaka R. and Tanaka H. | Additive beneficial effects of lactotripeptides and aerobic exercise on arterial compliance in postmenopausal women. | American Journal of Physiology Heart and Circulatory Physiology 2009; 297(5): H1899-1903. | Medline/ Cochrane |
14 | Yoshizawa M., Maeda S., Miyaki A., Misono M., Choi Y., Shimojo N., et al. | Additive beneficial effects of lactotripeptides intake with regular exercise on endothelium-dependent dilatation in postmenopausal women. | American Journal of Hypertension 2010; 23(4):368-372. | Medline/ Cochrane |
Included | Uchida, N., Ohsawa, K., Nakamura, T., Ohki, K., Amagai, S., Nakagawa, K., et al. | [Effect of Tablets Containing Lactotripeptides (Vpp, Ipp) on Vascular Endothelial Function in Healthy Subjects: A Randomized, Double‒Blind, Placebo‒Controlled Trial]. | Japanese Pharmacology & Therapeutics 2016; 44(7):1025-1034. Japanese. | J-DREAM III/J-STAGE |