Exclusion criteria

Authors

Title

Ref

Database

Included

Aihara K., Kajimoto O., Hirata H., Takahashi R., Nakamura Y.

Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension.

Journal of the American College of Nutrition 2005; 24(4):257-265.

Medline/ Cochrane

7

Hirota T., Ohki K., Kawagishi R., Kajimoto Y., Mizuno S., Nakamura Y. and Kitakaze M.

Casein hydrolysate containing the antihypertensive tripeptides Val-Pro-Pro and Ile-Pro-Pro improves vascular endothelial function independent of blood pressure-lowering effects: contribution of the

inhibitory action of angiotensin-converting enzyme.

Hypertension Research 2007; 30(6): 489-496.

Medline/ Cochrane

Included

Ishida Y., Aihara K., Sagitani A., Kaneko K., Mizutani J., Nakamura K., et al.

[Safety Evaluation of Excessive Intake of the Tablet Containing “Lactotripeptides (VPP, IPP)” in Subjects with Normal Blood Pressure to Mild Hypertension].

Japanese Pharmacology & Therapeutics 2006; 34:1107-1117. Japanese

J-DREAM III/ J-STAGE

Included

Ishida Y., Sagitani A., Kaneko K., Nakamura Y., Mizutani J., Masuda O.

[Antihypertensive Effects of the Tablet Containing “Lactotripeptide (VPP, IPP)” in Subjects with High Normal Blood Pressure to Mild Hypertension].

Japanese Pharmacology & Therapeutics 2007; 35(12):1249-1260. Japanese

J-DREAM III/ J-STAGE

Included

Ishida Y., Shibata Y., Fukuhara I., Yano Y., Takehara I., Kaneko K.

Effect of an excess intake of casein hydrolysate containing Val-Pro-Pro and Ile-Pro-Pro in subjects with normal blood pressure, high-normal blood pressure, or mild hypertension.

Bioscience, Biotechnology, and Biochemistry 2011; 75(3):427-433.

Medline/

Cochrane

Included

Itakura H., Ikemoto S., Terada S., Kondo K.

[The Effect of Sour Milk on Blood Pressure in Untreated Hypertensive and Normotensive

Subjects].

Journal of Japanese Society of Clinical Nutrition 2001; 23(3):26-31. Japanese

J-DREAM III/ J-STAGE

Included

Kajimoto O., Aihara K., Hirata H., Takahashi R., Nakamura Y.

[Safety evaluation of excessive intake of the tablet containing “Lactotripeptides (VPP, IPP)” on healthy volunteers].

Journal of Nutritional Food 2001; 4(4):37-46. Japanese

J-DREAM III/ J-STAGE

12

Kawase M., Hashimoto H., Hosoda M., Morita H. and Hosono A.

Effect of administration of fermented milk containing whey protein concentrate to rats and healthy men on serum lipids and blood pressure.

Journal of Dairy Science 2000; 83(2): 255-263.

Medline/ Cochrane

Included

Mizuno S., Matsuura K., Gotou T., Nishimura S., Kajimoto O., Yabune M., et al.

Antihypertensive effect of casein hydrolysate in a placebo-controlled study in subjects with high-normal blood pressure and mild hypertension.

The British Journal of Nutrition 2005; 94(1):84-91.

Medline/ Cochrane

14

Mizushima S., Ohshige K., Watanabe J., Kimura M., Kadowaki T., Nakamura Y., et al.

Randomized controlled trial of sour milk on blood pressure in borderline hypertensive men.

American Journal of Hypertension 2004; 17(8):701-706.

Medline/ Cochrane

Included

Nakamura Y., Kajimoto O., Kaneko K., Aihara K., Mizutani J., Ikeda N., et al.

[Effects of the liquid yogurts containing “lactotripeptide (VPP, IPP)” on high-normal blood pressure].

Journal of Nutritional Food 2004; 7(1):123-137. Japanese

J-DREAM III/ J-STAGE

Included

Sano J., Higuchi T., Aihara K., Mizuno S., Kajimoto O., Nakagawa S., et al.

[Safety evaluation of excessive intake of drink containing “lactotripeptides (VPP, IPP)” in subjects with normal blood pressure to mild hypertension].

Journal of Nutritional Food. 2004; 7(4):17-30. Japanese

J-DREAM III/ J-STAGE