Compounds

Activities

Mechanisms

Ref.(s)

Quercetrin, 3’,4’-Dimethoxyquercetin, Hirtacoumaroflavonoside and Hirtaflavonoside-B

Anti-diabetes

Inhibition of α-glucosidase, regulation of postprandial hyperglycemia

[27]

Quercetrin

Anti-diabetes

Pancreatic β cells MIN6-protective effect

[25]

Quercetin, rutin, myricitrin, cyanidin 3,5-O-diglucoside, Pelargonidin 3,5-diglucoside, α-amyrine, β-amyrine, taraxerol

Anti-diabetes

High binding affinity to protein relating diabetes Type 2

[42]

Myricitrin

Anti-viral

Inhibition of Japanese encephalitis virus

[28]

Galloylquinic acid

Anti-viral

Effective against NS1, NS3 and envelope proteins domain III of ZIKA virus

[43]

Euphorbianin and rutin

Anti-viral

High binding affinity against protease Mpro, RNA-dependent RNA polymerase RdRp of SARS-CoV-2

[44]

β-amyrin

Anti-inflammatory

iNOS protein inhibition on the LPS-induced RAW 264.7 cells

[35]

Quercetrin, Ferulic acid, Gallic acid and Rhamnetin

Anti-inflammatory

Effective against turpentine-induced arthritis, formalin-induced experimental peritonitis and cotton pellet-induced granuloma models to the rats

[18]

β-amyrin and 24-methyl encycloartenol β-sitosterol

Anti-inflammatory

Inhibition effects on TPA-induced inflammation in ear to the mice

[36]

Afzelin, Quercetrin and Myricitrin

Anticancer

Cytotoxic against human epidermoid carcinoma KB 3-1 cells

[24]

25-hydroperoxycycloart-23-en-3β-ol and 24-hydroperoxycycloart-25-en-3β-ol

Anticancer

Cytotoxicity against a human cancer cell line, colon carcinoma (HCT 116) and non-small cell lung adenocarcinoma

[34]

Quercetin

Anticancer

Cytotoxicity against human breast adenocarcinoma MCF-7 cells

[45]

Afzelin, Quercetrin and Myricitrin

Antimalarial

Proliferation inhibition of Plasmodium falciparum

[24]

Isorhamnetin and Pinocembrin

Antimalarial

Multiple plasmepsin protease inhibition

[46]

Taraxerol

Antimicrobial

Against Pseudomonas aeruginosa and Staphylococcus aureus

[34]

25-hydroperoxycycloart-23-en-3β-ol and 24-hydroperoxycycloart-25-en-3β-ol

Antimicrobial

Against P. aeruginosa, S. aureus and Escherichia coli, Candida albicans and Trichophyton mentagrophytes

[34]

quercetin and kaempferol

Antimicrobial

Against E. coli, P. aeruginosa, Proteus mirabilis, and S. aureus Aspergillus flavus, Aspergillus niger, T. mentagrophytes, and C. albicans

[22]

Taraxerone and 11α, 12α-oxidotaraxerol

Antimicrobial

Against Bacillus subtilis, B. cereus, B. megaterium, Sarcina lutea, S. aureus, E. coli, Shigella dysenteriae, S. sonnei, S. shiga, S. boydii, S. flexneriae, P. aeruginosa, Salmonella typhi, Klebsiella sp. Aspergillus flavus, A. niger, Penecillum sp. Trichoderma viride, C. albicans, Botryodiplodia theobromae

[14]

Caffeic acid and Epicatechin 3-gallate

Antimicrobial

Cellular membrane destruction and ensuing membrane permeability perturbation of P. aeruginosa

[12] [19]

Hydroquinone and O-coumaric acid

Antimicrobial

Against MRSA: S. aureus B39

[15]

Euphorbin C

Antimicrobial

Against Helicobacter pylori

[33]

β-Amyrin

Anti-atherosclerosis

Inhibition of atherosclerotic initiation induced by pro-inflammatory cytokines in SVEC4-10 endothelial cells

[47]

Quercetin

Antidiarrhoeic

Decrease both the total number of faeces and the number of diarrhoeic faeces induced in mice by castor oil

[13]

Quercetin

Anti-stress

Improvement in the swimming time, increases the time spent in open arm and decreases the time spent in the closed arm in mice

[23]

Taraxerol

Antiasthmatic

Inhibition of the contractile effect of histamine in guinea pigs

[37]

Hirtin

Anti-thrombotic disorders

Azocaseinolytic, gefibrinogenolytic, fibrinolytic and thrombin-like activities

[38]

Hydroxyl cinnamic acid derivatives

Antioxidant

Protection interaction with reference bovine serum albumin protein (BSA) against metal-catalyzed oxidation (MCO) system mediated oxidative damage

[20]

Methyl-3-(3,5- ditertbutyl-4-hydroxyphenyl) propionate

Antioxidant

DPPH radical scavenging activities in vitro

[39]

Twenty new chebulic acid and brevifolincarboxylic acid derivatives

Antioxidant

DPPH radical scavenging activities in vitro

[21]

Quercetrin

Anti-snake venom

Inhibition of protease, phospholipase-A2, hemolytic activity and hyaluronidase activities in vitro, inhibition in vivo of hemorrhage and edema induced in mice

[26]

Pyrogallol (1, 2,3-Benzenetriol)

Anti-snake venom

Inhibition of protease activity in vitro

[16]

Rutin

Anti-hemorrhoid

Remarkable healing on croton oil-inducing hemorrhoid in Wistar Albino rats

[29]