S

[45]

[46]

Q8NJT4

afl1

Fucose-specificlectin AFL 1

AFL is suggested to be the protein responsible for conidia attachment to the human lung epithelium. AFL is found from the sera of ABPA patients, has proinflammatory effect and is a possible virulence factor.

4

1

81

0.0000

Infinity

S

[1]

[38]

[47]

B0Y0Q7

Afu5g10570

cofilin

Ÿ Cofilin family proteins are essential regulators of actin cytoskeletal dynamics. Recent evidence also implicates cofilin in the regulation of mitochondrial function and stress responses. Charge alterations to conserved surfaces of cofilin that do not interfere with its actin regulatory activity lead to a dramatic increase in respiratory function that triggers upregulation of ABC transporters and metabolic changes that support multi-drug resistance

Ÿ Increased expression after voriconazole exposure

2

2

96

0.0101

24.71

R

[1]

[43]

[48]

B0Y6F1

Afu4g09600

GPI anchoredprotein, putative

Ÿ Genes regulated by SrbA, plays a role in ergosterol biosynthesis and which mediates resistance to azole antifungals (fluconazole susceptibility, lover voriconazole MIC in SrbA null mutant)

Ÿ Idi1 is connected to isoprenoid biosynthesis (precursors for biosynthesis of ergosterol)

13

12

1105

0.0012

1.96

S

B0Y8F7

idi1

isopentenyl-diphosphate delta-isomerase

4

4

162

0.0061

6.33

S

[1]

B0Y6V6

cafA

carbonicanhydrase

6

6

304

0.0316

7.84

R

[1]

B0YAM7

chiB1

class v chitinase 1, ChiB1

4

3

132

0.0033

4.31

R

[8]

DPP5

Afu2g09030

Dipeptidyl-peptidase 5 precursor (Dipeptidyl-peptidase V) (DppV)

8

8

301

0.0306

1.97

R

[49]

H31_ DEBHA

hht1

Histone H3.1/H3.2

4

1

127

0.0067

3.01

S

[1]

B0Y3U1

Afu5g07890

ssdna binding

4

3

116

0.0258

2.34

S

[1]

B0YC37

csx1

mRNA binding post-transcriptional regulator (Csx1), putative

1

1

52

0.0062

Infinity

S

[8]

[50]

NDK

ndk1

Nucleoside diphosphate kinase

S. cerevisiae ortholog (YNK1) plays a role in cellular response to DNA damage

8

8

363

0.0376

3.43