S | [45] [46] | Q8NJT4 | afl1 | Fucose-specificlectin AFL 1 | AFL is suggested to be the protein responsible for conidia attachment to the human lung epithelium. AFL is found from the sera of ABPA patients, has proinflammatory effect and is a possible virulence factor. | 4 | 1 | 81 | 0.0000 | Infinity |
S | [1] [38] [47] | B0Y0Q7 | Afu5g10570 | cofilin | Cofilin family proteins are essential regulators of actin cytoskeletal dynamics. Recent evidence also implicates cofilin in the regulation of mitochondrial function and stress responses. Charge alterations to conserved surfaces of cofilin that do not interfere with its actin regulatory activity lead to a dramatic increase in respiratory function that triggers upregulation of ABC transporters and metabolic changes that support multi-drug resistance Increased expression after voriconazole exposure | 2 | 2 | 96 | 0.0101 | 24.71 |
R | [1] [43] [48] | B0Y6F1 | Afu4g09600 | GPI anchoredprotein, putative | Genes regulated by SrbA, plays a role in ergosterol biosynthesis and which mediates resistance to azole antifungals (fluconazole susceptibility, lover voriconazole MIC in SrbA null mutant) Idi1 is connected to isoprenoid biosynthesis (precursors for biosynthesis of ergosterol) | 13 | 12 | 1105 | 0.0012 | 1.96 |
S | B0Y8F7 | idi1 | isopentenyl-diphosphate delta-isomerase | 4 | 4 | 162 | 0.0061 | 6.33 | ||
S | [1] | B0Y6V6 | cafA | carbonicanhydrase | 6 | 6 | 304 | 0.0316 | 7.84 | |
R | [1] | B0YAM7 | chiB1 | class v chitinase 1, ChiB1 | 4 | 3 | 132 | 0.0033 | 4.31 | |
R | [8] | DPP5 | Afu2g09030 | Dipeptidyl-peptidase 5 precursor (Dipeptidyl-peptidase V) (DppV) | 8 | 8 | 301 | 0.0306 | 1.97 | |
R | [49] | H31_ DEBHA | hht1 | Histone H3.1/H3.2 | 4 | 1 | 127 | 0.0067 | 3.01 | |
S | [1] | B0Y3U1 | Afu5g07890 | ssdna binding | 4 | 3 | 116 | 0.0258 | 2.34 | |
S | [1] | B0YC37 | csx1 | mRNA binding post-transcriptional regulator (Csx1), putative | 1 | 1 | 52 | 0.0062 | Infinity | |
S | [8] [50] | NDK | ndk1 | Nucleoside diphosphate kinase | S. cerevisiae ortholog (YNK1) plays a role in cellular response to DNA damage | 8 | 8 | 363 | 0.0376 | 3.43 |