Extracellular proteins

R

[1]

[32]

[33]

B0XPZ1

mep1

metalloprotease mep1

Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Plays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host in dermatophytes and dimorpic fungi.

3

3

143

0.0124

1.26

R

[1]

B0Y1L0

Afu5g01200, cp6

carboxypeptidase S1

3

3

153

0.0014

2.81

R

[1]

B0XYA1

Afu3g08930, sedC

tripeptidylpeptidase sed3

17

17

891

0.0133

1.29

S

[1]

B0Y226

pre6

proteasome component pre6

3

2

42

0.0103

9.30

S

[1]

[25]

[34]

[35]

B0Y5S8

metH

5-methyltetrahydropteroyl- triglutamate-homocysteine s-methyltransferase

Ÿ Putative cobalamin-independent methionine synthase; protein induced by heat shock

Ÿ Yap1-dependent induction in response to hydrogen peroxide (Yap1 is involved in the antioxidative stress response and antifungal drug resistance in C. albicans)

Ÿ Reacts with rabbit immunosera exposed to A. fumigatus conidia

15

14

624

0.0001

2.57

R

[1]

[36]

B0XYT5

gta1

glutaminase (nitrogenmetabolism)

Suggested as potential diagnostic target

10

10

701

0.0063

1.94

R

[1]

B0XPL9

Afu1g06470

neutral alkaline nonlysosomal ceramidase, putative

7

6

323

0.0358

1.88

R

[1]

B0XTM3

fmdS

formamidase

2

2

71

0.0021

1.85

R

[1]

B0XVH5

Afu2g05240

cytochrome cd1-nitrite reductase-c-terminal haem d1

8

8

474

0.0281

1.32

Oxidation-reduction

S

[1]

B0XV36

Afu2g04490

D-3-phosphoglycerate dehydrogenase

1

0

51

0.0123

S

[1]

[16]

[37]

B0Y871

Afu6g10260, akr1

aldehyde reductase (akr1)

Transcript up-regulated in conidia exposed to neutrophils and to human airway epithelial cells

2

2

42

0.0455

2.10

S

[1]

[38]

B0Y8P4

fmqD

fad binding domain protein

Downregulated in mycelia exposed to voriconazole

11

11

520

0.0035

1.67

S

[1]

B0Y9I5

AFUB_081170

oxidoreductase, putative

2

1

112

0.0015

Infinity

S

[8]

Q4WWK4

Afu_3g06190

cytochrome c oxidase subunit

2

2

102

0.0065

2.84

R

[1]

B0XYI5

Afu3g08070

GMC oxidoreductase, putative

2

2

102

0.0065

2.52

Protein binding

S

[1]

[39]

B0XPX0

Afu1g07540

26s proteasome regulatory particle subunit, Rpn8

Mutation confers hypersensitivity to amphotericin B in C. albicans RMN8

3

3

124

0.0121

3.49