Abundant condition (S/R)

Reference

protein

Systematic name

Seq. Description

Comment

Peptide count

Peptides used for quantitation

Confidence score

MinimalAnova (p)

Max fold change

Hydrophobins

R

[1]-[7]

B0XPA4

Afu1g17250

Conidial hydrophobin Rod B

Ÿ Surface proteins that confer hydrophobicity; Immunologically silence conidia

Ÿ RodA masks Dectin-1 and Dectin-2 recognition of conidia, resulting in impaired neutrophil recruitment, increased fungal survival and clinical disease; RodA strongly inhibits neutrophil extracellular trap formation

Ÿ Posaconazole concentrates within host cell membranes and rapidly transfers to A. fumigatus, where it accumulates. Transfer to conidia does not require phagocytosis, but is markedly enhanced by RodA.

Ÿ Important in adhesionto host (albumin and collagen)

4

4

336

0.0335

1.55

R

B0Y9E4

Afu8g07060

Hydrophobin, putative Rod C

12

12

1095

0.0004

1.99

R

RODL_ ASPFU

Afu5g09580

Hydrophobin precursor Rod A (Rodletprotein)

14

3

1785

0.0000

2794

R

H6SWN9

Hydrophobinrod A fragment

13

1

1624

0.0033

2.98

R

Q8TFV2

Hydrophobin hyp 1 fragment

9

1

1327

0.0001

2.48

R

Q8TFV8

Hydrophobin fragment

9

1

1237

0.0002

3.99

Translation/Ribosomal proteins

S

[1]

B0XQN8

Afu1g11190

eukaryotic translation elongation factor 1 subunit

7

6

588

0.0011

3.15

R

[1]

B0XR75

Afu1g12890

60s ribosomal protein l5

2

2

120

0.0370

1.21

S

[1]

B0XTE9

Afu2g13530

elongation factor 2

16

13

713

0.0106

1.60

S

[1]

B0XWG9

Afu2g13530

40s ribosomal protein s0

5

5

251

0.0004

3.68

S

[1]

B0Y372

Afu5g05630

60s ribosomal protein l23

3

3

93

0.0001

1.44

R

[1]

B0YBW2

Afu7g01460

40s ribosomal protein s5

3

3

117

0.0440

2.17

S

[1]

B0YD67

Afu6g03830

ribosomal protein l14

6

6

249

0.0062

1.57

S

[1]

B0YEB1

Afu4g04460

60s ribosomal protein l13

4

4

175

0.0312

2.01

S

[8]

Q4WWP9

Afu3g06640

40s ribosomal protein s27

2

2

108

0.0001

2.72

R

[1]

B0XYG2

Afu3g08290

aspartyl aminopeptidase

10

9

481

0.0015

1.12

S

[1]

B0XXQ3

Afu3g10920, stm1

telomere and ribosome associated protein Stm1, putative

3

3

64

0.0030

1.60

R

[8]

Q4WLQ8

Afu6g12660

40s ribosomal protein s10b

3

3

79

0.0410

1.52

S

[8]

Q4WRF2

Afu1g16523

40s ribosomal protein s25

4

4

181

0.0142

1.25