PARAMETER

VAL

HCTZ

VAL-1

VAL-2

HCTZ-1

HCTZ-2

HCTZ-3

LOD (μg/mL)

0.100

0.006

0.028

0.108

0.006

0.026

0.015

LOQ (μg/mL)

0.303

0.019

0.085

0.327

0.017

0.080

0.047

Correlation coefficient

0.9999

0.9998

0.9999

0.9999

1.0000

0.9999

1.0000

Bias at 100 % response

1.0368

−0.7663

0.6896

0.5841

−0.6679

0.6185

0.1819

Precision (%RSD)

1.3

1.3

1.6

1.2

1.3

0.8

0.9

Intermediate precision (%RSD)

1.2

1.4

1.3

1.9

1.5

1.6

0.8

Precision at LOQ (%RSD)

1.3

1.0

2.3

1.5

1.2

2.2

1.8