Stress condition (Degradation)

% of impurities formed

Peak purity†

HCTZ-1

HCTZ-2

HCTZ-3

HCTZ-4

VAL-1

VAL-2

Unknown

% Net degradation

20.520

RT

VAL

HCTZ

As such sample

0.1473

0.0277

0.0440

0.1279

0.0760

ND*

0.0283

N/A

999.848

999.993

Oxidation

0.1486

0.0254

0.0427

0.1334

0.0746

ND

0.0284

0.00

999.842

999.992

Acid

2.1784

0.0592

0.0419

0.0075

0.0752

ND

0.0285

2.01

999.843

999.993

Base

14.1829

0.1083

0.0365

0.0047

0.0747

ND

0.0286

13.99

999.838

999.994

Thermal

0.1471

0.0283

0.0433

0.1308

0.0760

ND

0.0256

0.00

999.832

999.993

Water

0.9975

0.0315

0.0423

0.0148

0.0754

ND

0.0291

0.76

999.834

999.994

UV

0.1470

0.0275

0.0415

0.1286

0.0754

ND

0.0257

0.00

999.841

999.993

SUN

0.1473

0.0290

0.0426

0.1310

0.0752

ND

0.0278

0.00

999.844

999.993

Humidity

0.1441

0.0234

0.0419

0.1189

0.0748

ND

0.0254

0.02

999.843

999.993