Characteristics (n, %) | Total (n = 130) | Mild/moderate (n = 110) | Severe (n = 20) | P |
Male | 64 (49.2) | 51 (46.4) | 13 (65.0) | 0.098 |
Age, MD ± SD, y | 54.4 ± 13.1 | 52.9 ± 13.1 | 60.1 ± 12.1 | 0.028 |
Comorbidities |
|
|
|
|
Hypertension | 31 (23.8) | 23 (20.9) | 8 (40.0) | 0.064 |
Diabetes | 18 (13.8) | 12 (10.9) | 6 (30.0) | 0.034 |
Coronary heart disease | 11 (8.5) | 7 (6.4) | 4 (20.0) | 0.066 |
Chronic liver disease | 10 (7.7) | 8 (7.3) | 2 (10.0) | 0.475 |
Chronic lung disease | 6 (4.6) | 4 (3.6) | 2 (10.0) | 0.230 |
Other | 31 (23.8) | 25 (22.7) | 6 (30.0) | 0.328 |
None | 55 (42.3) | 52 (47.3) | 3 (15.0) | 0.006 |
Symptoms |
|
|
|
|
Fever | 87 (66.9) | 69 (62.7) | 18 (90.0) | 0.012 |
Cough | 74 (56.9) | 58 (52.7) | 16 (80.0) | 0.019 |
Fatigue | 73 (56.2) | 58 (52.7) | 15 (75.0) | 0.052 |
Chest tightness | 54 (41.5) | 42 (38.2) | 12 (60.0) | 0.058 |
Diarrhea | 38 (29.2) | 35 (31.8) | 3 (15.0) | 0.101 |
Anorexia | 37 (28.5) | 29 (26.4) | 8 (40.0) | 0.165 |
Pharyngalgia | 16 (12.3) | 16 (14.5) | 0 | 0.070 |
Headache | 14 (10.8) | 14 (12.7) | 0 | 0.092 |
Myalgia | 8 (6.2) | 6 (5.5) | 2 (10.0) | 0.356 |
Asymptomatic | 10 (7.7) | 9 (8.2) | 1 (5.0) | 0.086 |
Positive CT and RT-PCR | 109 (83.8) | 92 (83.6) | 17 (85.0) | 0.590 |
Positive CT only | 14 (10.8) | 11 (10.0) | 3 (15.0) | 0.368 |
RNA negative conversion, d | 11.0 (6.0, 14.3) | 11.0 (6.0, 14.0) | 11.0 (2.8, 15.3) | 0.672 |
Obvious improvement of CT, d | 19.8 ± 8.8 | 19.3 ± 8.7 | 22.0 ± 8.9 | 0.219 |
Antiviral therapy |
|
|
|
|
Oseltamivir | 60 (46.2) | 52 (47.3) | 8 (40.0) | 0.550 |
Ribavirin | 24 (18.5) | 18 (16.4) | 6 (30.0) | 0.150 |
Abidor | 64 (49.2) | 59 (53.6) | 5 (25.0) | 0.019 |
Lianhua Qingwen | 73 (56.2) | 67 (60.9) | 6 (30.0) | 0.011 |
Peginterferon alfa-1b | 7 (5.4) | 4 (3.6) | 3 (15.0) | 0.039 |
Azithromycin | 29 (22.3) | 20 (18.2) | 9 (45.0) | 0.008 |
Moxifloxacin | 81 (62.3) | 66 (60.0) | 15 (75.0) | 0.153 |
Other antibiotics | 29 (22.3) | 23 (20.9) | 6 (30.0) | 0.265 |
Chinese herbal decoction | 48 (36.9) | 31 (28.2) | 17 (85.0) | 0.000 |
Hospital stay, d | 15.0 (10.3, 23.0) | 12.5 (8.3, 18.8) | 23.0 (16.0, 28.8) | 0.000 |